The cerebral cortex constitutes more than half the volume of the human brain and is
presumed to be responsible for the neuronal computations underlying complex phenomena …

The human CNS follows a pattern of development typical of all mammals, but certain
neurodevelopmental features are highly derived. Building the human CNS requires the …

The human brain develops slowly and over a long period of time which lasts for almost three
decades. This enables good spatio-temporal resolution of histogenetic and neurogenetic …

The most prominent transient compartment of the primate fetal cortex is the deep, cell-
sparse, synapse-containing subplate compartment (SPC). The developmental role of the …

The developing brain is extremely sensitive to many chemicals. Exposure to neurotoxicants
during development has been implicated in various neuropsychiatric and neurological …

This review summarizes early human brain development on the basis of neuroanatomical
data and functional connectomics. It indicates that the most significant changes in the brain …

Background Alzheimer's disease (AD) is a complex, irreversible neurodegenerative
disorder. At present there are neither reliable markers to diagnose AD at an early stage nor …

The analysis of animal models of neurological disease has been instrumental in furthering
our understanding of neurodevelopment and brain diseases. However, animal models are …

The brain of Down syndrome (DS) patients exhibits fewer interneurons in the cerebral
cortex, but its underlying mechanism remains unknown. By morphometric analysis of cortical …

The cerebral cortex forms early in development according to a series of heritable
neurodevelopmental instructions. Despite deep evolutionary conservation of the cerebral …