Regulation of reactive oxygen species-mediated damage in the pathogenesis of schizophrenia
S Madireddy, S Madireddy - Brain Sciences, 2020 - mdpi.com
The biochemical integrity of the brain is paramount to the function of the central nervous
system, and oxidative stress is a key contributor to cerebral biochemical impairment …
system, and oxidative stress is a key contributor to cerebral biochemical impairment …
Crosstalk between endoplasmic reticulum stress and oxidative stress in schizophrenia: The dawn of new therapeutic approaches
S Patel, D Sharma, K Kalia, V Tiwari - Neuroscience & Biobehavioral …, 2017 - Elsevier
Disruption of oxidant/anti-oxidant ratio as well as endoplasmic reticulum (ER) stress are
thought to be involved in the pathophysiology of schizophrenia. These stresses can lead to …
thought to be involved in the pathophysiology of schizophrenia. These stresses can lead to …
Diosgenin alleviates alcohol-mediated escalation of social defeat stress and the neurobiological sequalae
Rationale Emerging evidence indicates that persistent alcohol consumption escalates
psychosocial trauma achieved by social defeat stress (SDS)-induced neurobiological …
psychosocial trauma achieved by social defeat stress (SDS)-induced neurobiological …
Normalization of HPA axis, cholinergic neurotransmission, and inhibiting brain oxidative and inflammatory dynamics are associated with the adaptogenic-like effect of …
JOT Emudainohwo, B Ben-Azu, OG Adebayo… - Journal of Molecular …, 2023 - Springer
Social defeat stress (SDS) due to changes in biochemical functions has been implicated in
the pathogenesis of affective and cognitive disorders. Employing pharmacological approach …
the pathogenesis of affective and cognitive disorders. Employing pharmacological approach …
Lipopolysaccharide exacerbates ketamine-induced psychotic-like behavior, oxidative stress, and neuroinflammation in mice: ameliorative effect of diosmin
Schizophrenia, a neuropsychiatric disorder has been associated with aberrant
neurotransmission affecting behaviors, social preference, and cognition. Limitations in …
neurotransmission affecting behaviors, social preference, and cognition. Limitations in …
Mechanisms underpinning Carpolobia lutea G. Don ethanol extract's neurorestorative and antipsychotic-like activities in an NMDA receptor antagonist model of …
Ethnopharmacological relevance Persistent ketamine insults to the central nervous system
block NMDA receptors and disrupt putative neurotransmission, oxido–nitrosative, and …
block NMDA receptors and disrupt putative neurotransmission, oxido–nitrosative, and …
Season, storage and extraction method impact on the phytochemical profile of Terminalia ivorensis
Background Terminalia ivorensis (TI) is used in West African ethnomedicine for the
treatment of conditions including ulcers, malaria and wounds. Despite its widespread use …
treatment of conditions including ulcers, malaria and wounds. Despite its widespread use …
[HTML][HTML] Probable mechanisms involved in the antipsychotic-like activity of morin in mice
Evidence derived from preliminary studies suggests that morin, a neuroactive flavonoid with
proven antioxidant and antiinflammatory properties possess antipsychotic-like activity. The …
proven antioxidant and antiinflammatory properties possess antipsychotic-like activity. The …
Involvement of GABAergic, BDNF and Nox-2 mechanisms in the prevention and reversal of ketamine-induced schizophrenia-like behavior by morin in mice
GABAergic (Gamma-aminobutyric acid) and neurotrophic derangements have important
implication in schizophrenia, a neuropsychiatric disease. Previous studies have shown that …
implication in schizophrenia, a neuropsychiatric disease. Previous studies have shown that …
Berberine improves inhibitory avoidance memory impairment of Toxoplasma gondii-infected rat model of ketamine-induced schizophrenia
N Gholizadeh, A Dalimi, F Ghaffarifar… - … Medicine and Therapies, 2023 - Springer
Background Memory impairment caused by Toxoplasma gondii infection has been
documented. Berberine (BRB) is well known for its enhancing effects on memory and has …
documented. Berberine (BRB) is well known for its enhancing effects on memory and has …