Mechanisms of mitochondrial iron-sulfur protein biogenesis
R Lill, SA Freibert - Annual review of biochemistry, 2020 - annualreviews.org
Mitochondria are essential in most eukaryotes and are involved in numerous biological
functions including ATP production, cofactor biosyntheses, apoptosis, lipid synthesis, and …
functions including ATP production, cofactor biosyntheses, apoptosis, lipid synthesis, and …
[HTML][HTML] Mechanistic concepts of iron-sulfur protein biogenesis in Biology
JJ Braymer, SA Freibert, M Rakwalska-Bange… - Biochimica et Biophysica …, 2021 - Elsevier
Abstract Iron-sulfur (Fe/S) proteins are present in virtually all living organisms and are
involved in numerous cellular processes such as respiration, photosynthesis, metabolic …
involved in numerous cellular processes such as respiration, photosynthesis, metabolic …
Iron–sulfur cluster biogenesis and trafficking in mitochondria
JJ Braymer, R Lill - Journal of Biological Chemistry, 2017 - ASBMB
The biogenesis of iron–sulfur (Fe/S) proteins in eukaryotes is a multistage,
multicompartment process that is essential for a broad range of cellular functions, including …
multicompartment process that is essential for a broad range of cellular functions, including …
[HTML][HTML] Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease
Iron is a crucial transition metal for virtually all life. Two major destinations of iron within
mammalian cells are the cytosolic iron-storage protein, ferritin, and mitochondria. In …
mammalian cells are the cytosolic iron-storage protein, ferritin, and mitochondria. In …
Biosynthesis and function of posttranscriptional modifications of transfer RNAs
B El Yacoubi, M Bailly… - Annual review of …, 2012 - annualreviews.org
Posttranscriptional modifications of transfer RNAs (tRNAs) are critical for all core aspects of
tRNA function, such as folding, stability, and decoding. Most tRNA modifications were …
tRNA function, such as folding, stability, and decoding. Most tRNA modifications were …
[HTML][HTML] The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism
Mitochondria play a key role in iron metabolism in that they synthesize heme, assemble iron–
sulfur (Fe/S) proteins, and participate in cellular iron regulation. Here, we review the latter …
sulfur (Fe/S) proteins, and participate in cellular iron regulation. Here, we review the latter …
[HTML][HTML] Reprint of: Iron/sulfur proteins biogenesis in prokaryotes: formation, regulation and diversity
Iron/sulfur centers are key cofactors of proteins intervening in multiple conserved cellular
processes, such as gene expression, DNA repair, RNA modification, central metabolism and …
processes, such as gene expression, DNA repair, RNA modification, central metabolism and …
Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease
TA Rouault - Disease models & mechanisms, 2012 - journals.biologists.com
Iron-sulfur (Fe-S) clusters are ubiquitous cofactors composed of iron and inorganic sulfur.
They are required for the function of proteins involved in a wide range of activities, including …
They are required for the function of proteins involved in a wide range of activities, including …
Protein interactions in human pathogens revealed through deep learning
Identification of bacterial protein–protein interactions and predicting the structures of these
complexes could aid in the understanding of pathogenicity mechanisms and developing …
complexes could aid in the understanding of pathogenicity mechanisms and developing …
Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex
MT Boniecki, SA Freibert, U Mühlenhoff, R Lill… - Nature …, 2017 - nature.com
Abstract Iron–sulfur (Fe/S) clusters are essential protein cofactors crucial for many cellular
functions including DNA maintenance, protein translation, and energy conversion. De novo …
functions including DNA maintenance, protein translation, and energy conversion. De novo …