Prospects for Fluorescence Molecular In Vivo Liquid Biopsy of Circulating Tumor Cells in Humans
M Niedre - Frontiers in Photonics, 2022 - frontiersin.org
Our team recently developed “Diffuse in vivo Flow Cytometry”(DiFC) for detection and
enumeration rare circulating tumor cells (CTCs) in mice with highly-scattered fluorescent …
enumeration rare circulating tumor cells (CTCs) in mice with highly-scattered fluorescent …
Short-term circulating tumor cell dynamics in mouse xenograft models and implications for liquid biopsy
Motivation Circulating tumor cells (CTCs) are widely studied using liquid biopsy methods
that analyze fractionally-small peripheral blood (PB) samples. However, little is known about …
that analyze fractionally-small peripheral blood (PB) samples. However, little is known about …
Near-infrared diffuse in vivo flow cytometry
Significance Diffuse in vivo flow cytometry (DiFC) is an emerging technique for enumerating
rare fluorescently labeled circulating cells noninvasively in the bloodstream. Thus far, we …
rare fluorescently labeled circulating cells noninvasively in the bloodstream. Thus far, we …
Signal and measurement considerations for human translation of diffuse in vivo flow cytometry
Significance:“Diffuse in vivo flow cytometry”(DiFC) is an emerging technology for
fluorescence detection of rare circulating cells directly in large deep-seated blood vessels in …
fluorescence detection of rare circulating cells directly in large deep-seated blood vessels in …
Ratiometric fluorescence sensing and quantification of circulating blood sodium sensors in mice in vivo
In this work, we introduce ratiometric diffuse in vivo flow cytometry (R-DiFC) for quantitative
measurement of circulating fluorescent red blood cell (fRBC) sensors for systemic blood …
measurement of circulating fluorescent red blood cell (fRBC) sensors for systemic blood …
[HTML][HTML] In vivo growth of subclones derived from Lewis lung carcinoma is determined by the tumor microenvironment
BL Xu, XM Wang, GY Chen, P Yuan, L Han… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Heterogeneity is a fundamental feature of human tumors and plays a major role in drug
resistance and disease progression. In the present study, we selected single-cell-derived …
resistance and disease progression. In the present study, we selected single-cell-derived …
[HTML][HTML] Lipid nanoparticle encapsulated large peritoneal macrophages migrate to the lungs via the systemic circulation in a model of clodronate-mediated lung …
Rationale: A mature tissue resident macrophage (TRM) population residing in the peritoneal
cavity has been known for its unique ability to migrate to peritoneally located injured tissues …
cavity has been known for its unique ability to migrate to peritoneally located injured tissues …
Circulating tumor cells reveal early predictors of disease progression in patients with stage III NSCLC undergoing chemoradiation and immunotherapy
Circulating tumor cells (CTCs) are early signs of metastasis and can be used to monitor
disease progression well before radiological detection by imaging. Using an ultrasensitive …
disease progression well before radiological detection by imaging. Using an ultrasensitive …
Trends in Subcutaneous Tumour Height and Impact on Measurement Accuracy
D Brough, H Amos, K Turley, J Murkin - Cancer Informatics, 2023 - journals.sagepub.com
Tumour volume is typically calculated using only length and width measurements, using
width as a proxy for height in a 1: 1 ratio. When tracking tumour growth over time, important …
width as a proxy for height in a 1: 1 ratio. When tracking tumour growth over time, important …
Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity
Neonatal herpes simplex virus (nHSV) infections often result in significant mortality and
neurological morbidity despite antiviral drug therapy. Maternally transferred herpes simplex …
neurological morbidity despite antiviral drug therapy. Maternally transferred herpes simplex …