The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta‐analysis
Aims Deprescribing is a suggested intervention to reverse the potential iatrogenic harms of
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …
Deprescribing: a narrative review of the evidence and practical recommendations for recognizing opportunities and taking action
Deprescribing can be defined as the process of withdrawal or dose reduction of medications
which are considered inappropriate in an individual. The aim of this narrative review is to …
which are considered inappropriate in an individual. The aim of this narrative review is to …
Challenges and enablers of deprescribing: a general practitioner perspective
Aims Deprescribing is the process of reducing or discontinuing medicines that are
unnecessary or deemed to be harmful. We aimed to investigate general practitioner (GP) …
unnecessary or deemed to be harmful. We aimed to investigate general practitioner (GP) …
Deprescribing versus continuation of chronic proton pump inhibitor use in adults
TA Boghossian, W Thompson, V Welch… - Cochrane Database …, 2017 - cochranelibrary.com
Background Proton pump inhibitors (PPIs) are a class of medications that reduce acid
secretion and are used for treating many conditions such as gastroesophageal reflux …
secretion and are used for treating many conditions such as gastroesophageal reflux …
Proton pump inhibitors and the kidney: implications of current evidence for clinical practice and when and how to deprescribe
Proton pump inhibitors (PPIs), long thought to be safe, are associated with a number of
nonkidney adverse health outcomes and several untoward kidney outcomes, including …
nonkidney adverse health outcomes and several untoward kidney outcomes, including …
Deprescribing tools: a review of the types of tools available to aid deprescribing in clinical practice
E Reeve - Journal of pharmacy practice and research, 2020 - Wiley Online Library
The importance of deprescribing, which is the process of withdrawing an inappropriate
medication, supervised by a healthcare professional with the goal of managing …
medication, supervised by a healthcare professional with the goal of managing …
Barricades and brickwalls–a qualitative study exploring perceptions of medication use and deprescribing in long-term care
Background The co-administration of multiple drugs (polypharmacy) is the single most
common cause of adverse drug events in the older population, and residents of long-term …
common cause of adverse drug events in the older population, and residents of long-term …
DEFEAT-polypharmacy: deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities
Background Prolonged use of anticholinergic and sedative medicines is correlated with
worsening cognition and physical function decline. Deprescribing is a proposed intervention …
worsening cognition and physical function decline. Deprescribing is a proposed intervention …
Reduce unnecessary use of proton pump inhibitors
• Proton pump inhibitors (PPIs) are effective and widely used, but often for longer than
needed, adding to medication burden and resource waste• Discuss with patients reducing or …
needed, adding to medication burden and resource waste• Discuss with patients reducing or …
Recommendations for outcome measurement for deprescribing intervention studies
EA Bayliss, K Albers, K Gleason… - Journal of the …, 2022 - Wiley Online Library
Interpreting results from deprescribing interventions to generate actionable evidence is
challenging owing to inconsistent and heterogeneous outcome definitions between studies …
challenging owing to inconsistent and heterogeneous outcome definitions between studies …