Initial diagnostic workup of acute leukemia: guideline from the College of American Pathologists and the American Society of Hematology
DA Arber, MJ Borowitz, M Cessna… - … of pathology & …, 2017 - meridian.allenpress.com
Context.—A complete diagnosis of acute leukemia requires knowledge of clinical
information combined with morphologic evaluation, immunophenotyping and karyotype …
information combined with morphologic evaluation, immunophenotyping and karyotype …
Post-mortem whole-exome analysis in a large sudden infant death syndrome cohort with a focus on cardiovascular and metabolic genetic diseases
J Neubauer, MR Lecca, G Russo, C Bartsch… - European Journal of …, 2017 - nature.com
Sudden infant death syndrome (SIDS) is described as the sudden and unexplained death of
an apparently healthy infant younger than one year of age. Genetic studies indicate that up …
an apparently healthy infant younger than one year of age. Genetic studies indicate that up …
[HTML][HTML] Comparison of methods for the extraction of DNA from formalin-fixed, paraffin-embedded archival tissues
B Sengüven, E Baris, T Oygur… - International journal of …, 2014 - ncbi.nlm.nih.gov
Aim: Discussing a protocol involving xylene-ethanol deparaffinization on slides followed by
a kit-based extraction that allows for the extraction of high quality DNA from FFPE tissues …
a kit-based extraction that allows for the extraction of high quality DNA from FFPE tissues …
Identification of high-confidence somatic mutations in whole genome sequence of formalin-fixed breast cancer specimens
The utilization of archived, formalin-fixed paraffin-embedded (FFPE) tumor samples for
massive parallel sequencing has been challenging due to DNA damage and contamination …
massive parallel sequencing has been challenging due to DNA damage and contamination …
Robust gene expression and mutation analyses of RNA-sequencing of formalin-fixed diagnostic tumor samples
Current genomic studies are limited by the availability of fresh tissue samples. Here, we
show that Illumina RNA sequencing of formalin-fixed diagnostic tumor samples produces …
show that Illumina RNA sequencing of formalin-fixed diagnostic tumor samples produces …
Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis
SJ Kim, P Cheresh, RP Jablonski… - … of Physiology-Lung …, 2020 - journals.physiology.org
Alveolar epithelial cell (AEC) apoptosis, arising from mitochondrial dysfunction and
mitophagy defects, is important in mediating idiopathic pulmonary fibrosis (IPF). Our group …
mitophagy defects, is important in mediating idiopathic pulmonary fibrosis (IPF). Our group …
Thymoquinone protects the testes of hypothyroid rats by suppressing pro-inflammatory cytokines and oxidative stress and promoting SIRT1 testicular expression
SA Algaidi, KA Faddladdeen, GI Alrefaei… - Frontiers in …, 2022 - frontiersin.org
Background: Hypothyroidism has been linked to many testicular structural and dysfunctional
changes in males. Thymoquinone (TQ) has shown a potent testicular protective effect …
changes in males. Thymoquinone (TQ) has shown a potent testicular protective effect …
[HTML][HTML] Targeted or whole genome sequencing of formalin fixed tissue samples: potential applications in cancer genomics
S Munchel, Y Hoang, Y Zhao, J Cottrell, B Klotzle… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Current genomic studies are limited by the poor availability of fresh-frozen tissue samples.
Although formalin-fixed diagnostic samples are in abundance, they are seldom used in …
Although formalin-fixed diagnostic samples are in abundance, they are seldom used in …
Molecular investigation of possible relationships concerning bovine leukemia virus and breast cancer
Z Khan, M Abubakar, MJ Arshed, R Aslam, S Sattar… - Scientific reports, 2022 - nature.com
Worldwide, breast cancer has an eminent morbidity and mortality rate, as it is a neoplastic
disease among females. The query of the prospective danger of bovine leukemia virus …
disease among females. The query of the prospective danger of bovine leukemia virus …
[HTML][HTML] Data resources for the identification and interpretation of actionable mutations by clinicians
Following initial characterization of the reference human genome, initiatives have evolved
worldwide to identify genomic aberrations in cancer with the aim of deriving diagnostic …
worldwide to identify genomic aberrations in cancer with the aim of deriving diagnostic …