Metabolomics has grown into a prominent field contributing to the molecular understanding
of complex biological processes in both health and disease. Furthermore, single-cells are …

Owing to recent advances in mass spectrometry (MS), tens to hundreds of proteins, lipids,
and small molecules can be measured in single cells. The ability to characterize the …

Compositional diversity is a fundamental property in cell populations. Single‐cell analysis
promises new insight into this cellular heterogeneity on the genomic, transcriptomic …

Characterizing metabolism in cancer is crucial for understanding tumor biology and for
developing potential therapies. Although most metabolic investigations analyze averaged …

Single-cell metabolomics (SCM) is currently one of the most powerful tools for performing
high-throughput metabolic analysis at the cellular level. The power of single-cell …

Molecular analysis on the single-cell level represents a rapidly growing field in the life
sciences. While bulk analysis from a pool of cells provides a general molecular profile, it is …

The chemical differences between individual cells within large cellular populations provide
unique information on organisms' homeostasis and the development of diseased states …

Advances of analytical methods and emerging microfluidic tools have made it possible to
investigate biological processes in living organisms in detail and reach sensitivities sufficient …

Cells are the most basic structural units that play vital roles in the functioning of living
organisms. Analysis of the chemical composition and content of a single cell plays a vital …

This study describes a novel method for single-cell analysis and lipid profiling by combining
drop-on-demand inkjet cell printing and probe electrospray ionization mass spectrometry …