Glucose is the primary fuel to life on earth. Cellular uptake of glucose is a fundamental
process for metabolism, growth, and homeostasis. Three families of secondary glucose …

The cellular uptake of glucose is an essential physiological process, and movement of
glucose across biological membranes requires specialized transporters. The major facilitator …

The glucose transporter GLUT1 catalyses facilitative diffusion of glucose into erythrocytes
and is responsible for glucose supply to the brain and other organs. Dysfunctional mutations …

The major facilitator superfamily glucose transporters, exemplified by human GLUT1–4,
have been central to the study of solute transport. Using lipidic cubic phase crystallization …

Cancerous cells have an acutely increased demand for energy, leading to increased levels
of human glucose transporter 1 (hGLUT1). This up-regulation suggests hGLUT1 as a target …

Human glucose transporters (GLUTs) are responsible for cellular uptake of hexoses.
Elevated expression of GLUTs, particularly GLUT1 and GLUT3, is required to fuel the …

Neoplastic cells displayed altered metabolism with accelerated glycolysis. Therefore, these
cells need a mammoth supply of glucose for which they display an upregulated expression …

Glucose transporter (GLUT) 1 is found highly expressed in malignant tumors and considered
a mediator inducing cancer metastasis. Curcumin is a natural product which exerts anti …

The anaerobic metabolism of glucose by cancer cells, even under well-oxygenated
conditions, has been documented by Otto Warburg as early as 1927. Micro-environmental …

Introduction: Pathological complete response (pCR) rates of approximately 20% following
neoadjuvant long-course chemoradiotherapy for rectal cancer have given rise to non …