Mass spectrometry-based biomolecular analyses have become permanent fixtures of
academic, industrial, and clinical research settings. The rise in utilization of mass …

Owing to recent advances in mass spectrometry (MS), tens to hundreds of proteins, lipids,
and small molecules can be measured in single cells. The ability to characterize the …

Single-cell (SC) analysis provides unique insight into individual cell dynamics and cell-to-
cell heterogeneity. Here, we utilize trapped ion mobility separation coupled with dual …

Single-cell metabolomics hits its stride | Nature Methods Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Increasing evidence suggests that the spatial distribution of biomolecules within cells is a
critical component in deciphering single-cell molecular heterogeneity. State-of-the-art single …

Characterizing metabolism in cancer is crucial for understanding tumor biology and for
developing potential therapies. Although most metabolic investigations analyze averaged …

Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …

Technological innovations have transformed the way scientists approach biological and
clinical questions, transiting from conventional ensemble assays in bulk to emphasize on the …

Cells are the fundamental units of biological systems and exhibit unique development
trajectories and molecular features. Our exploration of how the genomes orchestrate the …

Subcellular omics: a new frontier pushing the limits of resolution, complexity and throughput |
Nature Methods Skip to main content Thank you for visiting nature.com. You are using a browser …