[HTML][HTML] The Effects of Viral Structural Proteins on Acidic Phospholipids in Host Membranes

R de Souza Cardoso, A Ono - Viruses, 2024 - mdpi.com
Enveloped viruses rely on host membranes for trafficking and assembly. A substantial body
of literature published over the years supports the involvement of cellular membrane lipids in …

A fatty acid-ordered plasma membrane environment is critical for Ebola virus matrix protein assembly and budding

S Amiar, KA Johnson, ML Husby, A Marzi… - Journal of Lipid …, 2024 - jlr.org
Plasma membrane (PM) domains and order phases have been shown to play a key role in
the assembly, release, and entry of several lipid-enveloped viruses. In the present study, we …

Minor electrostatic changes robustly increase VP40 membrane binding, assembly, and budding of Ebola virus matrix protein derived virus-like particles

BB Motsa, T Sharma, MD Cioffi, PP Chapagain… - Journal of Biological …, 2024 - ASBMB
Ebola virus (EBOV) is a filamentous negative-sense RNA virus, which causes severe
hemorrhagic fever. There are limited vaccines or therapeutics for prevention and treatment …

Computational and experimental identification of keystone interactions in Ebola virus matrix protein VP40 dimer formation

Y Narkhede, R Saxena, T Sharma, JP Conarty… - Protein …, 2024 - Wiley Online Library
The Ebola virus (EBOV) is a lipid‐enveloped virus with a negative sense RNA genome that
can cause severe and often fatal viral hemorrhagic fever. The assembly and budding of …

[HTML][HTML] PIP2 promotes the incorporation of CD43, PSGL-1 and CD44 into nascent HIV-1 particles

R de Souza Cardoso, T Murakami, B Jacobovitz… - …, 2024 - pmc.ncbi.nlm.nih.gov
Determinants regulating sorting of host transmembrane proteins at sites of enveloped virus
assembly on the plasma membrane (PM) remain poorly understood. Here, we demonstrate …

[HTML][HTML] Minor changes in electrostatics robustly increase VP40 membrane binding, assembly, and budding of Ebola virus matrix protein derived virus-like particles

BB Motsa, T Sharma, PP Chapagain, RV Stahelin - bioRxiv, 2024 - ncbi.nlm.nih.gov
Ebola virus (EBOV) is a filamentous negative-sense RNA virus which causes severe
hemorrhagic fever. There are limited vaccines or therapeutics for prevention and treatment …

Direct lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly

M Dutta, KA Dolan, S Amiar, EJ Bass, R Sultana… - bioRxiv, 2024 - biorxiv.org
M is the most abundant structural membrane protein in coronaviruses and is essential for the
formation of infectious virus particles. SARS-CoV-2 M adopts two conformations, Mshort and …