Inwardly rectifying K+ (Kir) channels allow K+ to move more easily into rather than out of the
cell. They have diverse physiological functions depending on their type and their location …

The endoplasmic reticulum (ER) has a quality-control system for'proof-reading'newly
synthesized proteins, so that only native conformers reach their final destinations. Non …

Calcitonin-gene-related peptide (CGRP) and adrenomedullin are related peptides with
distinct pharmacological profiles. Here we show that a receptor with seven transmembrane …

We report here the identification and characterization of a protein, ERIS, an endoplasmic
reticulum (ER) IFN stimulator, which is a strong type I IFN stimulator and plays a pivotal role …

The Spike (S) protein of SARS-CoV-2 binds ACE2 to direct fusion with host cells. S
comprises a large external domain, a transmembrane domain, and a short cytoplasmic tail …

Presumably because of the selective pressure exerted by the immune system, many viruses
have evolved proteins that interfere with antigen presentation by major histocompatibility …

Proper ion channel function often requires specific combinations of pore-forming α and
regulatory β subunits, but little is known about the mechanisms that regulate the surface …

The endoplasmic reticulum (ER) in animal cells is an extensive, morphologically continuous
network of membrane tubules and flattened cisternae. The ER is a multifunctional organelle; …

Cohen syndrome is an uncommon autosomal recessive disorder whose diagnosis is based
on the clinical picture of nonprogressive psychomotor retardation and microcephaly …

Surface expression of GABA B receptors requires heterodimerization of GB1 and GB2
subunits, but little is known about mechanisms that ensure efficient heterodimer assembly …