Our understanding of the evolution of DNA restriction and modification systems, the control
of the expression of the structural genes for the enzymes, and the importance of DNA …

BIOLOGY OF RESTRICTION AND MODIFICATION...................................... Restriction and
modification enzymes......................................................... Occurrence of RM …

Abstract In the early 1950's,'host-controlled variation in bacterial viruses' was reported as a
non-hereditary phenomenon: one cycle of viral growth on certain bacterial hosts affected the …

Restriction enzymes are well known as reagents widely used by molecular biologists for
genetic manipulation and analysis, but these reagents represent only one class (type II) of a …

Type I restriction enzymes (REases) are large pentameric proteins with separate restriction
(R), methylation (M) and DNA sequence-recognition (S) subunits. They were the first …

Merozoites of the malaria parasite Plasmodium falciparum carry surface proteins processed
from a precursor termed p190 or p195. Polymorphism has been reported in this protein …

The genes for over 100 restriction-modification systems have now been cloned, and
approximately one-half have been sequenced. Despite their similar function, they are …

The properties and sources of all known class-I, class-ll and class-Ill restriction
endonucleases (ENases) and DNA modification methyltransferases (MTases) are listed and …

Bacteria commonly endow their DNA with an identity mark. When DNA is transferred from
one bacterium to another strain of the same species, DNA that lacks the identification mark …

Epigenetic modifications such as DNA methylation have large effects on gene expression
and genome maintenance. Helicobacter pylori, a human gastric pathogen, has a large …