Evidence-based clinical practice guidelines for Liver Cirrhosis 2020

H Yoshiji, S Nagoshi, T Akahane, Y Asaoka… - Journal of …, 2021 - Springer
The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010,
and the second edition was published in 2015 by the Japanese Society of Gastroenterology …

Primary biliary cholangitis

A Lleo, GQ Wang, ME Gershwin, GM Hirschfield - The Lancet, 2020 - thelancet.com
Primary biliary cholangitis is an autoimmune liver disease that predominantly affects women.
It is characterised by a chronic and destructive, small bile duct, granulomatous lymphocytic …

Efficacy and safety of elafibranor in primary biliary cholangitis

KV Kowdley, CL Bowlus, C Levy… - … England Journal of …, 2024 - Mass Medical Soc
Background Primary biliary cholangitis is a rare, chronic cholestatic liver disease
characterized by the destruction of interlobular bile ducts, leading to cholestasis and liver …

A phase 3 trial of seladelpar in primary biliary cholangitis

GM Hirschfield, CL Bowlus, MJ Mayo… - … England Journal of …, 2024 - Mass Medical Soc
Background Effective treatments for patients with primary biliary cholangitis are limited.
Seladelpar, a peroxisome proliferator–activated receptor delta agonist, has potential …

EASL Clinical Practice Guidelines on sclerosing cholangitis

O Chazouilleres, U Beuers, A Bergquist, TH Karlsen… - Journal of …, 2022 - Elsevier
Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

AASLD practice guidance on primary sclerosing cholangitis and cholangiocarcinoma

CL Bowlus, L Arrivé, A Bergquist, M Deneau… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …

Novel therapeutic targets for cholestatic and fatty liver disease

M Trauner, CD Fuchs - Gut, 2022 - gut.bmj.com
Cholestatic and non-alcoholic fatty liver disease (NAFLD) share several key
pathophysiological mechanisms which can be targeted by novel therapeutic concepts that …

[HTML][HTML] A randomized placebo-controlled trial of elafibranor in patients with primary biliary cholangitis and incomplete response to UDCA

JM Schattenberg, A Pares, KV Kowdley… - Journal of …, 2021 - Elsevier
Background & Aims Patients with primary biliary cholangitis (PBC) who have an incomplete
response to ursodeoxycholic acid remain at risk of disease progression. We investigated the …

APASL clinical practice guidance: the diagnosis and management of patients with primary biliary cholangitis

H You, X Ma, C Efe, G Wang, SH Jeong, K Abe… - Hepatology …, 2022 - Springer
Hong You1· Xiong Ma2· Cumali Efe3· Guiqiang Wang4· Sook‑Hyang Jeong5· Kazumichi
Abe6· Weijia Duan1· Sha Chen1· Yuanyuan Kong7· Dong Zhang8· Lai Wei9· Fu‑Sheng …

[HTML][HTML] Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study

GM Hirschfield, ML Shiffman, A Gulamhusein… - Hepatology, 2023 - journals.lww.com
Seladelpar efficacy and safety at 3 months in patients with... : Hepatology Seladelpar
efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a …