[HTML][HTML] Complex interplay between autophagy and oxidative stress in the development of pulmonary disease
W Ornatowski, Q Lu, M Yegambaram, AE Garcia… - Redox biology, 2020 - Elsevier
The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …
Mammalian autophagy: how does it work?
CF Bento, M Renna, G Ghislat, C Puri… - Annual review of …, 2016 - annualreviews.org
Autophagy is a conserved intracellular pathway that delivers cytoplasmic contents to
lysosomes for degradation via double-membrane autophagosomes. Autophagy substrates …
lysosomes for degradation via double-membrane autophagosomes. Autophagy substrates …
Type I photosensitizers based on phosphindole oxide for photodynamic therapy: apoptosis and autophagy induced by endoplasmic reticulum stress
Z Zhuang, J Dai, M Yu, J Li, P Shen, R Hu, X Lou… - Chemical …, 2020 - pubs.rsc.org
Photodynamic therapy (PDT) is considered a pioneering and effective modality for cancer
treatment, but it is still facing challenges of hypoxic tumors. Recently, Type I PDT, as an …
treatment, but it is still facing challenges of hypoxic tumors. Recently, Type I PDT, as an …
Regulation mechanisms and signaling pathways of autophagy
C He, DJ Klionsky - Annual review of genetics, 2009 - annualreviews.org
Autophagy is a process of self-degradation of cellular components in which double-
membrane autophagosomes sequester organelles or portions of cytosol and fuse with …
membrane autophagosomes sequester organelles or portions of cytosol and fuse with …
Plasma membrane contributes to the formation of pre-autophagosomal structures
B Ravikumar, K Moreau, L Jahreiss, C Puri… - Nature cell …, 2010 - nature.com
Autophagy is a catabolic process in which lysosomes degrade intracytoplasmic contents
transported in double-membraned autophagosomes. Autophagosomes are formed by the …
transported in double-membraned autophagosomes. Autophagosomes are formed by the …
[HTML][HTML] Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic …
EL Axe, SA Walker, M Manifava, P Chandra… - The Journal of cell …, 2008 - ncbi.nlm.nih.gov
Autophagy is the engulfment of cytosol and organelles by double-membrane vesicles
termed autophagosomes. Autophagosome formation is known to require …
termed autophagosomes. Autophagosome formation is known to require …
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation
Autophagy is a bulk degradation process in eukaryotic cells and has fundamental roles in
cellular homeostasis. The origin and source of autophagosomal membranes are long …
cellular homeostasis. The origin and source of autophagosomal membranes are long …
Mitochondria supply membranes for autophagosome biogenesis during starvation
Starvation-induced autophagosomes engulf cytosol and/or organelles and deliver them to
lysosomes for degradation, thereby resupplying depleted nutrients. Despite advances in …
lysosomes for degradation, thereby resupplying depleted nutrients. Despite advances in …
Cell death assays for drug discovery
Cell death has an important role in many human diseases, and strategies aimed at
modulating the associated pathways have been successfully applied to treat various …
modulating the associated pathways have been successfully applied to treat various …
An overview of macroautophagy in yeast
X Wen, DJ Klionsky - Journal of molecular biology, 2016 - Elsevier
Macroautophagy is an evolutionarily conserved dynamic pathway that functions primarily in
a degradative manner. A basal level of macroautophagy occurs constitutively, but this …
a degradative manner. A basal level of macroautophagy occurs constitutively, but this …