The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …

The human gut microbiota has now been associated with drug responses and efficacy, while
chemical compounds present in these drugs can also impact the gut bacteria. However …

Functional constipation is common in children and adults worldwide. Functional constipation
shows similarities in children and adults, but important differences also exist regarding …

Chronic constipation is a prevalent functional gastrointestinal disorder accompanied with
intestinal dysbiosis. However, causal relationship between dysbiosis and constipation …

Chronic constipation (CC) is a highly prevalent and burdensome gastrointestinal disorder.
Accumulating evidence highlights the link between imbalances in the gut microbiome and …

Objective To evaluate the effectiveness and safety of nonpharmacologic interventions for the
treatment of childhood functional constipation. Study design Randomized controlled trials …

Functional constipation (FC) is considered the most common functional gastrointestinal
disorder in children with a pooled global prevalence of 14.4%(95% confidence interval: 11.2 …

Lactobacillus rhamnosus GG (LGG) is a well-known probiotic widely used in foods and
drugs. It has been reported that LGG can improve bowel dysfunction in gastrointestinal …

We updated our 2010 systematic review on the efficacy of probiotics in the treatment of
constipation in children. The MEDLINE, EMBASE, and Cochrane Library databases; clinical …