Intracellular and intercellular signaling networks in cancer initiation, development and precision anti-cancer therapy: RAS acts as contextual signaling hub

P Csermely, T Korcsmáros, R Nussinov - Seminars in cell & developmental …, 2016 - Elsevier
Cancer initiation and development are increasingly perceived as systems-level phenomena,
where intra-and inter-cellular signaling networks of the ecosystem of cancer and stromal …

An enriched network motif family regulates multistep cell fate transitions with restricted reversibility

Y Ye, X Kang, J Bailey, C Li, T Hong - PLoS computational biology, 2019 - journals.plos.org
Multistep cell fate transitions with stepwise changes of transcriptional profiles are common to
many developmental, regenerative and pathological processes. The multiple intermediate …

Local and global features of genetic networks supporting a phenotypic switch

A Shomar, O Barak, N Brenner - Plos one, 2020 - journals.plos.org
Phenotypic switches are associated with alterations in the cell's gene expression profile and
are vital to many aspects of biology. Previous studies have identified local motifs of the …

Avaliação histológica dos brotamentos peritumorais no câncer colorretal

MRM SOUTO MAIOR - 2017 - repositorio.ufpe.br
O câncer colorretal (CCR) é uma das neoplasias malignas com maior incidência e
mortalidade no mundo. Uma das medidas mais importantes na busca de maiores índices de …

[引用][C] Intracellular and intercellular signaling networks in

PCTKR Nussinov - development, 2016