Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies
K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …
personalized medicine. This review covers the principles, advantages, and drawbacks of …
Michael addition reactions in macromolecular design for emerging technologies
The Michael addition reaction is a versatile synthetic methodology for the efficient coupling
of electron poor olefins with a vast array of nucleophiles. This review outlines the role of the …
of electron poor olefins with a vast array of nucleophiles. This review outlines the role of the …
Degradable poly (β-amino esters): synthesis, characterization, and self-assembly with plasmid DNA
Poly (β-aminoesters) 1− 3 were synthesized via the addition of N, N '-
dimethylethylenediamine, piperazine, and 4, 4 '-trimethylenedipiperidine to 1, 4-butanediol …
dimethylethylenediamine, piperazine, and 4, 4 '-trimethylenedipiperidine to 1, 4-butanediol …
Recent progress in polymer-based platinum drug delivery systems
Platinum drugs comprise of almost 50% of all currently used anticancer drugs. They are now
widely used in the clinical therapy of various solid tumors, including ovarian, head and neck …
widely used in the clinical therapy of various solid tumors, including ovarian, head and neck …
PLGA–mPEG nanoparticles of cisplatin: in vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood properties
K Avgoustakis, A Beletsi, Z Panagi… - Journal of controlled …, 2002 - Elsevier
The in vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in
blood properties of PLGA–mPEG nanoparticles of cisplatin were investigated. The …
blood properties of PLGA–mPEG nanoparticles of cisplatin were investigated. The …
Poly (amido‐amine) s: Biomedical Applications
P Ferruti, MA Marchisio… - Macromolecular Rapid …, 2002 - Wiley Online Library
Abstract Poly (amido‐amine) s (PAAs) are synthetic tert‐amino polymers obtained by
stepwise polyaddition of primary or secondary aliphatic amines to bis (acrylamide) s. Linear …
stepwise polyaddition of primary or secondary aliphatic amines to bis (acrylamide) s. Linear …
Cisplatin-loaded polymer-metal complex micelle with time-modulated decaying property as a novel drug delivery system
Purpose. The pharmacological activity and pharmacokinetics of cisplatin (CDDP)-loaded
polymeric micelles were examined to reveal their usefulness as a novel tumor-directed drug …
polymeric micelles were examined to reveal their usefulness as a novel tumor-directed drug …
Characterization and applications of new hyper-cross-linked cyclodextrins
F Trotta, R Cavalli - Composite interfaces, 2009 - Taylor & Francis
Nanosponges are recently developed hyper-cross-linked cyclodextrin polymers
nanostructured to form 3-dimensional networks; they are obtained by reacting cyclodextrin …
nanostructured to form 3-dimensional networks; they are obtained by reacting cyclodextrin …
Anticancer activity of cisplatin-loaded PLGA-mPEG nanoparticles on LNCaP prostate cancer cells
EC Gryparis, M Hatziapostolou, E Papadimitriou… - European journal of …, 2007 - Elsevier
The in vitro anticancer activity of cisplatin-loaded PLGA-mPEG nanoparticles on human
prostate cancer LNCaP cells was investigated. The uptake of the PLGA-mPEG nanoparticles …
prostate cancer LNCaP cells was investigated. The uptake of the PLGA-mPEG nanoparticles …
Preparation and evaluation of nanoparticles made of chitosan or N-trimethyl chitosan and a cisplatin–alginate complex
In this work, nanoparticles with a negative or positive surface charge were prepared through
electrostatic interaction of an anionic cisplatin–alginate complex with a cationic …
electrostatic interaction of an anionic cisplatin–alginate complex with a cationic …