Lipid-based nanoformulations in the treatment of neurological disorders
The neurological disorders affect millions of people worldwide, and are bracketed as the
foremost basis of disability-adjusted life years (DALYs). The treatment options are …
foremost basis of disability-adjusted life years (DALYs). The treatment options are …
Novel nanotechnology-based approaches for targeting HIV reservoirs
Highly active anti-retroviral therapy (HAART) is prescribed for HIV infection and, to a certain
extent, limits the infection's spread. However, it cannot completely eradicate the latent virus …
extent, limits the infection's spread. However, it cannot completely eradicate the latent virus …
[HTML][HTML] Etravirine-loaded dissolving microneedle arrays for long-acting delivery
A key challenge of HIV treatment with multiple antiretroviral drugs is patient adherence.
Thus, there is an urgent need for long-acting depot systems for delivering drugs over an …
Thus, there is an urgent need for long-acting depot systems for delivering drugs over an …
Insights on oral drug delivery of lipid nanocarriers: a win-win solution for augmenting bioavailability of antiretroviral drugs
The therapeutic functionality of innumerable antiretroviral drugs is supposedly obscured
owing to their low metabolic stability in the gastrointestinal tract and poor solubilization …
owing to their low metabolic stability in the gastrointestinal tract and poor solubilization …
Development of novel S PC-3 gefitinib lipid nanoparticles for effective drug delivery in breast cancer. Tissue distribution studies and cell cytotoxicity analysis
S Nayek, NM Raghavendra, BS Kumar - Journal of drug delivery science …, 2021 - Elsevier
Objective The present work was aimed to develop gefitinib solid lipid nanoparticles (GFT-
SLN) using novel lipids (Lipoid S PC-3) and to analyse its cell cytotoxicity and tissue …
SLN) using novel lipids (Lipoid S PC-3) and to analyse its cell cytotoxicity and tissue …
[HTML][HTML] Nanostructured lipid carriers (NLCs)-based intranasal Drug Delivery System of Tenofovir disoproxil fumerate (TDF) for brain targeting
Brain is one of the dominant reservoirs of HIV. Blood Brain Barrier (BBB) provides a great
challenge in the delivery of Tenofovir disoproxil fumerate (TDF) to CNS after systemic …
challenge in the delivery of Tenofovir disoproxil fumerate (TDF) to CNS after systemic …
Recent techniques and patents on solid lipid nanoparticles as novel carrier for drug delivery
The various approaches have been utilized in the treatment of a variety of diseases by
applying drug delivery system such as polymeric nanoparticles, self-emulsifying delivery …
applying drug delivery system such as polymeric nanoparticles, self-emulsifying delivery …
Lipid Based Aqueous Core Nanocapsules (ACNs) for Encapsulating Hydrophillic Vinorelbine Bitartrate: Preparation, Optimization, Characterization and In vitro Safety …
Background: Vinorelbine bitartrate (VRL) is an antimitotic agent approved by FDA for breast
cancer and non-small cell lung cancer (NSCLC) in many countries. However, high aqueous …
cancer and non-small cell lung cancer (NSCLC) in many countries. However, high aqueous …
Envisioning the prospect of nanocarriers as an effective management tool against NeuroAIDS
Antiretroviral Therapy (ART) has significantly enhanced the life expectancy of individuals
living with HIV, yet it has introduced novel challenges such as drug resistance, HIV …
living with HIV, yet it has introduced novel challenges such as drug resistance, HIV …
Improvement in bioavailability and pharmacokinetic characteristics of efavirenz with booster dose of ritonavir in PEGylated PAMAM G4 dendrimers
R Kharwade, S More, E Suresh, A Warokar… - AAPS …, 2022 - Springer
Efavirenz (EFV) with a booster dose of ritonavir (RTV)(EFV-RTV) inhibits the metabolism of
EFV and improves its bioavailability. However, inadequate organ perfusion with surface …
EFV and improves its bioavailability. However, inadequate organ perfusion with surface …