Consensus paper. Cerebellar reserve: from cerebellar physiology to cerebellar disorders

H Mitoma, A Buffo, F Gelfo, X Guell, E Fucà, S Kakei… - The Cerebellum, 2020 - Springer
Cerebellar reserve refers to the capacity of the cerebellum to compensate for tissue damage
or loss of function resulting from many different etiologies. When the inciting event produces …

Blood levels of brain-derived neurotrophic factor (BDNF) in people with multiple sclerosis (MS): A systematic review and meta-analysis

N Karimi, H Ashourizadeh, BA Pasha… - Multiple Sclerosis and …, 2022 - Elsevier
Background Multiple sclerosis is an autoimmune demyelinating disease marked by the
involvement of multiple pathophysiological pathways, including BDNF. BDNF (brain-derived …

Effects of exercise training on multiple sclerosis biomarkers of central nervous system and disease status: a systematic review of intervention studies

R Negaresh, RW Motl, P Zimmer… - European journal of …, 2019 - Wiley Online Library
Background and purpose Multiple sclerosis (MS) is a demyelinating and neurodegenerative
disease of the central nervous system (CNS) that can be tracked through biomarkers of …

Aerobic exercise increases irisin serum levels and improves depression and fatigue in patients with relapsing remitting multiple sclerosis: a randomized controlled trial

F Bilek, N Cetisli-Korkmaz, Z Ercan, G Deniz… - Multiple sclerosis and …, 2022 - Elsevier
Background Multiple sclerosis (MS) is a chronic progressive neurodegenerative disease of
the central nervous system. Although there is increasing evidence that aerobic exercise has …

Effectiveness of blood flow‐restricted slow walking on mobility in severe multiple sclerosis: A pilot randomized trial

N Lamberti, S Straudi, M Donadi… - … journal of medicine …, 2020 - Wiley Online Library
Objective We tested the safety, feasibility, and effectiveness of blood flow restriction‐
empowered low‐intensity interval walking exercise (BFR‐W) compared with conventional …

Fitness shifts the balance of BDNF and IL-6 from inflammation to repair among people with progressive multiple sclerosis

AJ Devasahayam, LP Kelly, JB Williams, CS Moore… - Biomolecules, 2021 - mdpi.com
Physical sedentarism is linked to elevated levels of circulating cytokines, whereas exercise
upregulates growth-promoting proteins such as brain-derived neurotrophic factor (BDNF) …

The MoxFo initiative—Mechanisms of action: Biomarkers in multiple sclerosis exercise studies

SC Rosenkranz, M Ploughman… - Multiple Sclerosis …, 2023 - journals.sagepub.com
Background: As exercise exerts neurobiological and immunomodulatory effects, it might also
act as a disease-modifying intervention in MS. However, a clear mechanistic link between …

Prolonged cortical silent period is related to poor fitness and fatigue, but not tumor necrosis factor, in multiple sclerosis

AR Chaves, LP Kelly, CS Moore, M Stefanelli… - Clinical …, 2019 - Elsevier
Objective Poor fitness among people with Multiple Sclerosis (MS) aggravates disease
symptoms. Whether low fitness levels accompany brain functioning changes is unknown …

Effects of non-pharmacological interventions on gait and balance of persons with Multiple Sclerosis: A narrative review

M Parsaei, M Amanollahi, F TaghaviZanjani… - Multiple Sclerosis and …, 2024 - Elsevier
Abstract Background Multiple Sclerosis (MS) is among the most common reasons for
disability in young adults. Mobility impairment, primarily related to gait and balance, is …

Walking training enhances corticospinal excitability in progressive multiple sclerosis—a pilot study

AR Chaves, AJ Devasahayam… - Frontiers in …, 2020 - frontiersin.org
Background: Inflammatory lesions and neurodegeneration lead to motor, cognitive, and
sensory impairments in people with multiple sclerosis (MS). Accumulation of disability is at …