Urine proteomics and renal single‐cell transcriptomics implicate interleukin‐16 in lupus nephritis

A Fava, DA Rao, C Mohan, T Zhang… - Arthritis & …, 2022 - Wiley Online Library
Objective Current lupus nephritis (LN) treatments are effective in only 30% of patients,
emphasizing the need for novel therapeutic strategies. We undertook this study to develop …

Epigenetic dysregulation in autoimmune and inflammatory skin diseases

F Gibson, A Hanly, N Grbic, N Grunberg, M Wu… - Clinical Reviews in …, 2022 - Springer
Epigenetics is the study of heritable, reversible gene expression patterns that do not
originate from alterations in the DNA sequence. Epigenetic modifications influence gene …

[HTML][HTML] Whole-exome sequencing identified genetic risk factors for asparaginase-related complications in childhood ALL patients

R Abaji, V Gagné, CJ Xu, JF Spinella, F Ceppi… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Allergy, pancreatitis and thrombosis are common side-effects of childhood acute
lymphoblastic leukemia (ALL) treatment that are associated with the use of asparaginase …

Genetic polymorphism of interleukin-16 influences susceptibility to HBV-related hepatocellular carcinoma in a Chinese population

S Li, Y Deng, ZP Chen, S Huang, XC Liao… - Infection, Genetics and …, 2011 - Elsevier
Aim: Interleukin-16 (IL16) as a multifunctional cytokine, plays a key role in inflammatory and
autoimmune diseases as well as tumour growth and progression. Recently, genetic …

The role of IL‑16 gene polymorphisms in endometriosis

M Matalliotakis, MI Zervou… - international …, 2018 - spandidos-publications.com
Endometriosis is one of the most common gynecological diseases affecting up to 10% of the
female population of childbearing age and a major cause of pain and infertility. It is …

[PDF][PDF] Comparison of oral lichen planus and systemic lupus erythematosus in interleukins level

HF AGHA, MS MOOSAVI, TM HAJIFARAJ - 2015 - sid.ir
Lichen planus (LP) is a chronic in. ammatory mucocutaneous disorder with unknown
etiology. Systemic lupus erythematosus (SLE) is known as a prototypic autoimmune …

Polymorphisms in proinflammatory cytokines genes and susceptibility to Multiple Sclerosis

NM Bakr, NA Hashim, HAED El-Baz, EM Khalaf… - Multiple Sclerosis and …, 2021 - Elsevier
Background Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative
disorder of the central nervous system (CNS). It is immunologically induced in genetically …

IL‐1β and IL‐6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype

Y Wu, B Cai, J Zhang, B Shen, Z Huang… - Journal of …, 2017 - Wiley Online Library
Background. Systemic lupus erythematosus (SLE) is an autoimmune disease with great
heterogeneity in pathogenesis and clinical symptoms. Rheumatoid factor (RF) is one key …

[PDF][PDF] Interleukin-16 (IL-16) gene polymorphisms in Iranian patients with colorectal cancer.

P Azimzadeh, S Romani, SR Mohebbi… - … of Gastrointestinal & …, 2011 - researchgate.net
Background & Aims: A number of theories have been put forward to clarify the etiology of
colorectal cancer (CRC), such as genetic alterations and cytokine production. A combination …

Association between interleukin 6 and interleukin 16 gene polymorphisms and coronary heart disease risk in a Chinese population

Z Tong, Q Li, J Zhang, Y Wei… - Journal of international …, 2013 - journals.sagepub.com
Objective To investigate the role of interleukin 6 (IL6) and IL16 single nucleotide
polymorphisms (SNPs) in coronary artery disease (CAD) risk in a Chinese population …