[HTML][HTML] HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation

L Chia, B Wang, JH Kim, LZ Luo… - The Journal of …, 2023 - Am Soc Clin Investig
High mobility group A1 (HMGA1) chromatin regulators are upregulated in diverse tumors
where they portend adverse outcomes, although how they function in cancer remains …

Apoptosis and heart failure: The role of non-coding RNAs and exosomal non-coding RNAs

K Li, L Ma, Z Lu, L Yan, W Chen, B Wang, H Xu… - … -Research and Practice, 2023 - Elsevier
Heart failure is a condition that affects the cardio vascular system and occurs if the heart
cannot adequately pump the oxygen and blood to the body. Myocardial infarction …

Landmark series: the cancer genome atlas and the study of breast cancer disparities

JA Johnson, BJ Moore, G Syrnioti, CM Eden… - Annals of Surgical …, 2023 - Springer
Race-related variation in breast cancer incidence and mortality are well-documented in the
United States. The effect of genetic ancestry on disparities in tumor genomics, risk factors …

HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression

L Li, JH Kim, W Lu, DM Williams, J Kim… - Blood, The Journal …, 2022 - ashpublications.org
Myeloproliferative neoplasms (MPNs) transform to myelofibrosis (MF) and highly lethal acute
myeloid leukemia (AML), although the actionable mechanisms driving progression remain …

[HTML][HTML] Expression, tumor immune infiltration, and prognostic impact of HMGs in gastric cancer

Z Wu, Y Huang, W Yuan, X Wu, H Shi, M Lu… - Frontiers in …, 2022 - frontiersin.org
Background In the past decade, considerable research efforts on gastric cancer (GC) have
been expended, however, little advancement has been made owing to the lack of effective …

[HTML][HTML] ST8SIA6-AS1 contributes to hepatocellular carcinoma progression by targeting miR-142-3p/HMGA1 axis

T Feng, Y Yao, L Luo, H Zou, G Xiang, L Wei, Q Yang… - Scientific reports, 2023 - nature.com
Hepatocellular carcinoma (LIHC) accounts for 90% of all liver cancers and is a serious
health concern worldwide. Long noncoding RNAs (lncRNAs) have been observed to …

[HTML][HTML] High mobility group A1 (HMGA1): structure, biological function, and therapeutic potential

L Wang, J Zhang, M Xia, C Liu, X Zu… - International journal of …, 2022 - ncbi.nlm.nih.gov
High mobility group A1 (HMGA1) is a nonhistone chromatin structural protein characterized
by no transcriptional activity. It mainly plays a regulatory role by modifying the structure of …

High expression of OSR1 as a predictive biomarker for poor prognosis and lymph node metastasis in breast cancer

Y Li, J Qin, J Wu, X Dai, J Xu - Breast cancer research and treatment, 2020 - Springer
Purpose Oxidative stress-responsive kinase 1 (OSR1) plays a crucial role in regulating
diverse cellular pathophysiologic functions, including ion homeostasis, development …

[HTML][HTML] HMGA1, moonlighting protein function, and cellular real estate: location, location, location!

M Pujals, L Resar, J Villanueva - Biomolecules, 2021 - mdpi.com
The gene encoding the High Mobility Group A1 (HMGA1) chromatin remodeling protein is
upregulated in diverse cancers where high levels portend adverse clinical outcomes. Until …

[HTML][HTML] LncRNA MALAT1 aggravates oxygen‐glucose deprivation/reoxygenation-induced neuronal endoplasmic reticulum stress and apoptosis via the miR-195a-5p …

Y Jia, L Yi, Q Li, T Liu, S Yang - Biological Research, 2021 - Springer
Background This study aimed to investigate the potential role and molecular mechanism of
lncRNA metastasis associated lung adenocarcinoma transcript 1 (MALAT1) in cerebral …