In vitro production of infectious Plasmodium falciparum sporozoites

AG Eappen, T Li, M Marquette, S Chakravarty, N Kc… - Nature, 2022 - nature.com
An effective vaccine is needed for the prevention and elimination of malaria. The only
immunogens that have been shown to have a protective efficacy of more than 90% against …

Vector population monitoring tools for insecticide resistance management: myth or fact?

J Vontas, K Mavridis - Pesticide biochemistry and physiology, 2019 - Elsevier
Insecticide resistance is a large and growing problem for the control of mosquito disease
vectors. The World Health Organization (WHO) established the Global Plan for Insecticide …

Highly sensitive droplet digital PCR-based diagnostics for the surveillance of malaria vector populations in low transmission and incipient resistance settings

K Mavridis, K Michaelidou, J Vontas - Expert review of molecular …, 2021 - Taylor & Francis
ABSTRACT Background Sensitive monitoring of Plasmodium infective mosquitoes in low
malaria transmission settings is of high priority for disease control. Early detection of …

Anopheles parensis contributes to residual malaria transmission in South Africa

A Burke, Y Dahan-Moss, F Duncan, B Qwabe… - Malaria journal, 2019 - Springer
Background Understanding the contribution of outdoor-resting Anopheles mosquitoes to
residual malaria transmission is important in terms of scaling up vector control towards …

Rapid multiplex gene expression assays for monitoring metabolic resistance in the major malaria vector Anopheles gambiae

K Mavridis, N Wipf, S Medves, I Erquiaga, P Müller… - Parasites & vectors, 2019 - Springer
Background Metabolic resistance of the major malaria vector Anopheles gambiae (sl) to
insecticides is operationally significant, particularly in combination with target site resistance …

Detection and Monitoring of Insecticide Resistance Mutations in Anopheles gambiae: Individual vs. Pooled Specimens

K Mavridis, N Wipf, P Müller, MM Traoré, G Muller… - Genes, 2018 - mdpi.com
Bioassays and molecular diagnostics are routinely used for the monitoring of malaria vector
populations to support insecticide resistance management (IRM), guiding operational …

Evaluating the stability of host-reference gene expression and simultaneously quantifying parasite burden and host immune responses in murine malaria

DJ Browne, AM Kelly, J Brady, C Proietti… - Scientific Reports, 2023 - nature.com
The efficacy of pre-erythrocytic stage malaria antigens or vaccine platforms is routinely
assessed in murine models challenged with Plasmodium sporozoites. Relative liver-stage …

Detection of malaria sporozoites expelled during mosquito sugar feeding

VA Brugman, M Kristan, MP Gibbins, F Angrisano… - Scientific reports, 2018 - nature.com
Malaria is a severe disease of global importance transmitted by mosquitoes of the genus
Anopheles. The ability to rapidly detect the presence of infectious mosquitoes able to …

A comparison of PCR and ELISA methods to detect different stages of Plasmodium vivax in Anopheles arabiensis

AL Hendershot, E Esayas, AC Sutcliffe, SR Irish… - Parasites & …, 2021 - Springer
Background In characterizing malaria epidemiology, measuring mosquito infectiousness
informs the entomological inoculation rate, an important metric of malaria transmission. PCR …

Converging human and malaria vector diagnostics with data management towards an integrated holistic one health approach

K Mitsakakis, S Hin, P Müller, N Wipf… - International journal of …, 2018 - mdpi.com
Monitoring malaria prevalence in humans, as well as vector populations, for the presence of
Plasmodium, is an integral component of effective malaria control, and eventually …