Clinical trial principles and endpoint definitions for paravalvular leaks in surgical prosthesis

CE Ruiz, RT Hahn, A Berrebi, JS Borer… - European heart …, 2018 - academic.oup.com
Abstract The VARC (Valve Academic Research Consortium) for transcatheter aortic valve
replacement set the standard for selecting appropriate clinical endpoints reflecting safety …

Transcatheter closure of paravalvular leaks: state of the art

I Cruz-Gonzalez, JC Rama-Merchan… - Netherlands Heart …, 2017 - Springer
Paravalvular leak (PVL) is a serious complication after surgical valve replacement or after
transcatheter aortic valve replacement. Approximately 1–5% of PVLs can lead to serious …

Techniques and outcomes for the treatment of paravalvular leak

MF Eleid, AK Cabalka, JF Malouf, S Sanon… - Circulation …, 2015 - Am Heart Assoc
2 Eleid et al Techniques for Treatment of Paravalvular Leak necessary to make a definitive
diagnosis, exclude LA thrombus, evaluate prosthetic function, characterize the severity of …

[HTML][HTML] Outcomes and predictors of success and complications for paravalvular leak closure: an analysis of the SpanisH real-wOrld paravalvular LEaks closure …

E García, D Arzamendi… - …, 2017 - eurointervention.pcronline.com
Aims: The aim of the study was to assess the safety and efficacy of percutaneous closure of
paravalvular prosthetic leak (PVL) and to identify the predictors of procedural success and …

Techniques and outcomes of percutaneous aortic paravalvular leak closure

M Alkhouli, M Sarraf, E Maor, S Sanon… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives: The aim of this study is to provide a summary of the currently applied aortic
paravalvular leak (PVL) closure techniques and describe the procedural and long-term …

Paravalvular leaks—from diagnosis to management

S Bernard, E Yucel - Current treatment options in cardiovascular medicine, 2019 - Springer
Purpose of review As the number of surgical and transcatheter valve replacements continue
to increase in the aging population, so does the incidence of paravalvular leak (PVL). Given …

Outcomes after paravalvular leak closure: transcatheter versus surgical approaches

JA Wells, JF Condado, N Kamioka, A Dong… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: The aim of this study was to compare outcomes of transcatheter intervention (TI)
versus surgical intervention (SI) for paravalvular leak (PVL). Background: Data comparing …

Percutaneous paravalvular leak closure: chasing the chameleon

F Nietlispach, F Maisano, P Sorajja… - European heart …, 2016 - academic.oup.com
Paravalvular leak (PVL) occurs after both surgical and transcatheter valve replacement/
implantation. It can lead to haemolysis, heart failure and may increase the risk of …

[HTML][HTML] Long-term results after surgical treatment of paravalvular leak in the aortic and mitral position

I Bouhout, A Mazine, A Ghoneim, X Millàn… - The Journal of Thoracic …, 2016 - Elsevier
Objectives The aim of this study was to determine immediate results and long-term
outcomes after surgical management of paravalvular leak (PVL). Methods Between 1995 …

Aortic valve disease, transcatheter aortic valve replacement, and the heart failure patient: a state-of-the-art review

N Okumus, S Abraham, R Puri, WHW Tang - Heart Failure, 2023 - jacc.org
Concomitant aortic stenosis (AS) in heart failure (HF) is associated with high rates of
mortality and morbidity. Current guidelines recommend aortic valve replacement in patients …