The role of macronutrients, micronutrients and flavonoid polyphenols in the prevention and treatment of osteoporosis

M Martiniakova, M Babikova, V Mondockova, J Blahova… - Nutrients, 2022 - mdpi.com
Osteoporosis is considered an age-related disorder of the skeletal system, characterized
primarily by decreased bone mineral density (BMD), microstructural quality and an elevated …

The role of menaquinones (vitamin K2) in human health

JWJ Beulens, SL Booth… - British journal of …, 2013 - cambridge.org
Recent reports have attributed the potential health benefits of vitamin K beyond its function
to activate hepatic coagulation factors. Moreover, several studies have suggested that …

The role of vitamin K in humans: implication in aging and age-associated diseases

DS Popa, G Bigman, ME Rusu - Antioxidants, 2021 - mdpi.com
As human life expectancy is rising, the incidence of age-associated diseases will also
increase. Scientific evidence has revealed that healthy diets, including good fats, vitamins …

Calcium, vitamin D, vitamin K2, and magnesium supplementation and skeletal health

A Capozzi, G Scambia, S Lello - Maturitas, 2020 - Elsevier
Supplementation with calcium (Ca) and/or vitamin D (vitD) is key to the management of
osteoporosis. Other supplements like vitamin K2 (VitK2) and magnesium (Mg) could …

[HTML][HTML] Menaquinones, bacteria, and the food supply: the relevance of dairy and fermented food products to vitamin K requirements

B Walther, JP Karl, SL Booth, P Boyaval - Advances in nutrition, 2013 - Elsevier
Vitamin K exists in the food supply as phylloquinone, a plant-based form and as
menaquinones (MKs), a collection of isoprenologues mostly originating from bacterial …

Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women

MHJ Knapen, NE Drummen, E Smit, C Vermeer… - Osteoporosis …, 2013 - Springer
We have investigated whether low-dose vitamin K2 supplements (menaquinone-7, MK-7)
could beneficially affect bone health. Next to an improved vitamin K status, MK-7 …

Vitamin K and osteoporosis: myth or reality?

A Palermo, D Tuccinardi, L D'Onofrio, M Watanabe… - Metabolism, 2017 - Elsevier
Vitamin K is a liposoluble vitamin. The predominant dietary form, phylloquinone or vitamin
K1, is found in plants and green vegetables; whereas menaquinone, or vitamin K2, is …

[HTML][HTML] 25-Hydroxyvitamin D as a biomarker of vitamin D status and its modeling to inform strategies for prevention of vitamin D deficiency within the population

KD Cashman, EGHM van den Heuvel… - Advances in …, 2017 - Elsevier
There is substantial evidence that the prevalence of vitamin D deficiency is unacceptably
high in the population, and this requires action from a public health perspective. Circulating …

Effect of vitamin K in bone metabolism and vascular calcification: A review of mechanisms of action and evidences

JKD Villa, MAN Diaz, VR Pizziolo… - Critical reviews in food …, 2017 - Taylor & Francis
Osteoporosis is a public health concern associated with an increased risk of bone fractures
and vascular calcification. Vitamin K presents unique benefits on these issues, although …

Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials

ZB Huang, SL Wan, YJ Lu, L Ning, C Liu… - Osteoporosis …, 2015 - Springer
To identify the role of vitamin K2 for the prevention and treatment of osteoporosis in
postmenopausal women, we conducted this meta-analysis of 19 randomized controlled …