[HTML][HTML] The role of the gut microbiome in the healthy adult status

V D'Argenio, F Salvatore - Clinica chimica acta, 2015 - Elsevier
The gut microbiome, which hosts up to 1000 bacterial species that encode about 5 million
genes, perform many of the functions required for host physiology and survival …

A view to a kill: the bacterial type VI secretion system

BT Ho, TG Dong, JJ Mekalanos - Cell host & microbe, 2014 - cell.com
The bacterial type VI secretion system (T6SS) is an organelle that is structurally and
mechanistically analogous to an intracellular membrane-attached contractile phage tail …

Dual RNA-seq of pathogen and host

AJ Westermann, SA Gorski, J Vogel - Nature Reviews Microbiology, 2012 - nature.com
A comprehensive understanding of host–pathogen interactions requires a knowledge of the
associated gene expression changes in both the pathogen and the host. Traditional, probe …

An infection-relevant transcriptomic compendium for Salmonella enterica Serovar Typhimurium

C Kröger, A Colgan, S Srikumar, K Händler… - Cell host & …, 2013 - cell.com
Bacterial transcriptional networks consist of hundreds of transcription factors and thousands
of promoters. However, the true complexity of transcription in a bacterial pathogen and the …

Resolving host–pathogen interactions by dual RNA-seq

AJ Westermann, L Barquist, J Vogel - PLoS pathogens, 2017 - journals.plos.org
The transcriptome is a powerful proxy for the physiological state of a cell, healthy or
diseased. As a result, transcriptome analysis has become a key tool in understanding the …

Requirements for Pseudomonas aeruginosa Acute Burn and Chronic Surgical Wound Infection

KH Turner, J Everett, U Trivedi, KP Rumbaugh… - PLoS …, 2014 - journals.plos.org
Opportunistic infections caused by Pseudomonas aeruginosa can be acute or chronic. While
acute infections often spread rapidly and can cause tissue damage and sepsis with high …

A microbial transporter of the dietary antioxidant ergothioneine

DG Dumitrescu, EM Gordon, Y Kovalyova… - Cell, 2022 - cell.com
Summary Low-molecular-weight (LMW) thiols are small-molecule antioxidants required for
the maintenance of intracellular redox homeostasis. However, many host-associated …

Bacterial RNA biology on a genome scale

J Hör, SA Gorski, J Vogel - Molecular cell, 2018 - cell.com
Bacteria are an exceedingly diverse group of organisms whose molecular exploration is
experiencing a renaissance. While the classical view of bacterial gene expression was …

Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence

BW Davies, RW Bogard, TS Young, JJ Mekalanos - Cell, 2012 - cell.com
The function of the Vibrio 7 th pandemic island-1 (VSP-1) in cholera pathogenesis has
remained obscure. Utilizing chromatin immunoprecipitation sequencing and RNA …

Cross-species RNA-seq for deciphering host–microbe interactions

AJ Westermann, J Vogel - Nature Reviews Genetics, 2021 - nature.com
The human body is constantly exposed to microorganisms, which entails manifold
interactions between human cells and diverse commensal or pathogenic bacteria. The …