Phospholipase D: enzymology, functionality, and chemical modulation

PE Selvy, RR Lavieri, CW Lindsley, HA Brown - Chemical reviews, 2011 - ACS Publications
Phosphatidic acid (PA) is a critical phospholipid constituent in eukaryotic cell membranes,
which accounts for 1À4% of the total lipid. 1 This lipophilic glycerophospholipid has a …

Phospholipase D as a catalyst: application in phospholipid synthesis, molecular structure and protein engineering

J Damnjanović, Y Iwasaki - Journal of bioscience and bioengineering, 2013 - Elsevier
Phospholipase D (PLD) is a useful enzyme for its transphosphatidylation activity, which
enables the enzymatic synthesis of various phospholipids (PLs). Many reports exist on PLD …

Imidazole-functionalized pillar [5] arenes: highly reactive and selective supramolecular artificial enzymes

EH Wanderlind, DG Liz, AP Gerola, RF Affeldt… - ACS …, 2018 - ACS Publications
Phosphate diester hydrolysis is strongly accelerated, by a factor of 104, in the presence of
artificial enzymes especially designed in the light of spatiotemporal concepts, anchoring …

Task-specific ionic liquid incorporating anionic heteropolyacid-catalyzed Hantzsch and Mannich multicomponent reactions. Ionic liquid effect probed by ESI-MS (/MS)

HGO Alvim, GA Bataglion, LM Ramos, AL de Oliveira… - Tetrahedron, 2014 - Elsevier
A task-specific ionic liquid with a Bronsted acid (1-(3-sulfopropyl)-3-methylimidazolium
hydrogen sulfate, namely MSI) bearing an anionic heteropolyacid derivative ([PW 12 O 40] …

Transformation of a Cp*–Iridium (III) Precatalyst for Water Oxidation when Exposed to Oxidative Stress

C Zuccaccia, G Bellachioma, O Bortolini… - … A European Journal, 2014 - Wiley Online Library
Abstract The reaction of [Cp* Ir (bzpy) NO3](1; bzpy= 2‐benzoylpyridine, Cp*=
pentamethylcyclopentadienyl anion), a competent water‐oxidation catalyst, with several …

Tunable pH-sensitive linker for controlled release

CJ Choy, JJ Geruntho, AL Davis… - Bioconjugate …, 2016 - ACS Publications
We have developed a novel pH-sensitive linker based on a phosphoramidate scaffold that
can be tuned to release amine-containing drug molecules at various pH values. The pH …

Molecular structure of phospholipase D and regulatory mechanisms of its activity in plant and animal cells

YS Kolesnikov, KP Nokhrina, SV Kretynin… - Biochemistry …, 2012 - Springer
Phospholipase D (PLD) catalyzes hydrolysis of phospholipids with production of
phosphatidic acid, which often acts as secondary messenger of transduction of intracellular …

Imidazole-functionalized Y-shaped push–pull dye for nerve agent sensing as well as a catalyst for their detoxification

N Dey, J Kulhanek, F Bures… - The Journal of Organic …, 2021 - ACS Publications
A Y-shaped push–pull dye (1) with N, N-dimethylanilino donors and a benzonitrile acceptor
connected via an imidazole-based π-conjugated spacer was designed. It showed a dark …

Charge-tagged acetate ligands as mass spectrometry probes for metal complexes investigations: Applications in Suzuki and Heck phosphine-free reactions

FFD Oliveira, MR dos Santos, PM Lalli… - The Journal of …, 2011 - ACS Publications
An acetate anion bearing an imidazolium cation as its charge tag was reacted with M (OAc)
2 complexes (where M= Ni, Cu, and Pd; in situ reaction) to form members of a new class of …

Second-generation tunable pH-sensitive phosphoramidate-based linkers for controlled release

CJ Choy, CR Ley, AL Davis, BS Backer… - Bioconjugate …, 2016 - ACS Publications
We developed a second generation of tunable pH-sensitive linkers based on our
phosphoramidate scaffold to release amine-containing drugs under acidic conditions. The …