The self controlled case series (SCCS) method is an epidemiological study design for which
individuals act as their own control—ie, comparisons are made within individuals. Hence …

These updated guidelines from the British Association for Psychopharmacology replace the
original version published in 2011. They address the scope and targets of pharmacological …

People with severe mental illness have a considerably shorter lifespan than the general
population. This excess mortality is mainly due to physical illness. Next to mental illness …

Self-Controlled Case Series Studies: A Modelling Guide with R provides the first
comprehensive account of the self-controlled case series (SCCS) method, a statistical …

Objective To investigate whether there is an association between use of ACE inhibitors
(ACEI) and angiotensin receptor blockers (ARB) and risk of acute kidney injury (AKI). Study …

Background The effect of antipsychotic (AP) drugs on risk of stroke and myocardial infarction
(MI) remains unclear due to methodological limitations of, and inconsistencies across …

Objective To investigate the association between antipsychotic drug use and the
development of first-time seizures in patients with schizophrenia, affective disorders, or …

Introduction: Although antipsychotics have been associated with sudden cardiac death
(SCD), they still remain a cornerstone in the treatment of psychiatric patients. Most …

Observational studies have been recognised to be essential for investigating the safety
profile of medications. Numerous observational studies have been conducted on the …

Background Acetaminophen (APAP) is frequently used for analgesia and is considered
safer than nonsteroidal anti-inflammatory drugs (NSAIDs) for the kidneys. However, there is …