The various therapeutic applications of the medical isotope holmium-166: a narrative review

NJM Klaassen, MJ Arntz, A Gil Arranja… - EJNMMI radiopharmacy …, 2019 - Springer
Over the years, a broad spectrum of applications of the radionuclide holmium-166 as a
medical isotope has been established. The isotope holmium-166 is attractive as it emits high …

Cutting edge rare earth radiometals: prospects for cancer theranostics

AWE Sadler, L Hogan, B Fraser… - EJNMMI Radiopharmacy …, 2022 - Springer
Background With recent advances in novel approaches to cancer therapy and imaging, the
application of theranostic techniques in personalised medicine has emerged as a very …

Neutron-activated theranostic radionuclides for nuclear medicine

HY Tan, CH Yeong, YH Wong, M McKenzie… - Nuclear medicine and …, 2020 - Elsevier
Theranostics in nuclear medicine refers to personalized patient management that involves
targeted therapy and diagnostic imaging using a single or combination of radionuclide (s) …

Radiochemical processing of nuclear-reactor-produced radiolanthanides for medical applications

M Van de Voorde, K Van Hecke, T Cardinaels… - Coordination Chemistry …, 2019 - Elsevier
Several radiolanthanides find their application in nuclear medicine because of their
favorable decay properties, the most important ones being 143 Pr, 149 Pm, 153 Sm, 165 Dy …

Pharmaceutical and clinical development of phosphonate-based radiopharmaceuticals for the targeted treatment of bone metastases

R Lange, R Ter Heine, RFF Knapp, JMH de Klerk… - Bone, 2016 - Elsevier
Therapeutic phosphonate-based radiopharmaceuticals radiolabeled with beta, alpha and
conversion electron emitting radioisotopes have been investigated for the targeted treatment …

Targeted radionuclide therapy of painful bone metastases: past developments, current status, recent advances and future directions

A Dash, T Das, FFR Knapp - Current medicinal chemistry, 2020 - ingentaconnect.com
Bone pain arising from secondary skeletal malignancy constitutes one of the most common
types of chronic pain among patients with cancer which can lead to rapid deterioration of the …

Production and clinical applications of radiopharmaceuticals and medical radioisotopes in Iran

AR Jalilian, D Beiki, A Hassanzadeh-Rad… - Seminars in Nuclear …, 2016 - Elsevier
During past 3 decades, nuclear medicine has flourished as vibrant and independent
medical specialty in Iran. Since that time, more than 200 nuclear physicians have been …

[HTML][HTML] Production, quality control and biological evaluation of 166Ho-PDTMP as a possible bone palliation agent

S Zolghadri, AR Jalilian, Z Naseri… - Iranian Journal of …, 2013 - ncbi.nlm.nih.gov
Objective (s): In this study, 166 Ho-1, 2-propylene di-amino tetra (
methy1enephosphonicAcid)(166 Ho-PDTMP) complex was prepared as a bone palliation …

[HTML][HTML] 177Lu-EDTMP radiation absorbed dose evaluation in man based on biodistribution data in Wistar rats

R Bagheri - Nuclear Engineering and Technology, 2023 - Elsevier
Skeletal metastases are common in patients suffering from various primary cancers.
Radiopharmaceuticals are an effective option for bone pain palliation. In this work, the …

[HTML][HTML] Advances in radionuclides and radiolabelled peptides for cancer therapeutics

K Chakraborty, J Mondal, JM An, J Park, YK Lee - Pharmaceutics, 2023 - mdpi.com
Radiopharmaceutical therapy, which can detect and treat tumours simultaneously, was
introduced more than 80 years ago, and it has changed medical strategies with respect to …