The development of new ion-activation/dissociation methods continues to be one of the most
active areas of mass spectrometry owing to the broad applications of tandem mass …

Photodissociation mass spectrometry combines the ability to activate and fragment ions
using photons with the sensitive detection of the resulting product ions by mass …

Surveillance of the extracellular environment by immune receptors is of central importance
to eukaryotic survival. The rice receptor kinase XA21, which confers robust resistance to …

Native mass spectrometry (nMS) is evolving into a workhorse for structural biology. The
plethora of online and offline preparation, separation, and purification methods as well as …

The analysis of peptides and proteins as well as the grander scope of proteomics (large
scale study of proteins) has been advanced by the development of a versatile array of ion …

Plants and animals sense conserved microbial signatures through receptors localized to the
plasma membrane and cytoplasm. These receptors typically carry or associate with non …

Diclofenac (DCF) is a widely used non-steroidal anti-inflammatory pharmaceutical which is
detected in the environment at concentrations which can pose a threat to living organisms. In …

Most existing directed evolution methods, both in vivo,, and in vitro,,, suffer from inadvertent
selective pressures (ie, altering organism fitness), resulting in the evolution of products with …

METHODS Herein we describe alternative dissociation methods commonly employed within
mass spectrometry with an emphasis on the outcomes of probing native protein complexes …

Sulfated peptides are plant hormones that are active at nanomolar concentrations. The
sulfation at one or more tyrosine residues is catalysed by tyrosylprotein sulfotransferase …