Mitochondria are critical organelles for endocrine health; steroid hormone biosynthesis
occurs in these organelles and they provide energy in the form of ATP for hormone …

Mitochondria are dynamic cellular organelles responsible for a large variety of biochemical
processes as energy transduction, REDOX signaling, the biosynthesis of hormones and …

Rare diseases affect nearly 300 million people globally with most patients aged five or less.
Traditional diagnostic approaches have provided much of the diagnosis; however, there are …

Abstract Objective Single Large Scale Mitochondrial DNA Deletions (SLSMDs), Pearson
Syndrome (PS) and Kearns-Sayre Syndrome (KSS), are systemic diseases with multiple …

Background Electrolyte reabsorption in the kidney has a high energy demand. Proximal and
distal tubular epithelial cells have a high mitochondrial density for energy release. Recently …

Cortisol is central to several homeostatic mechanisms including the stress and immune
response. Adrenal insufficiency and impaired cortisol production leads to severe, potentially …

Diabetes and hyperglycemia are common features of mitochondrial disorders. This study
investigates the frequency of non-iatrogenic hypoglycemia in individuals with these …

GFER-related mitochondrial encephalomyopathy has been previously described only in 3
siblings of a consanguineous Moroccan family. Their phenotype included congenital …

Headache is a prominent feature in mitochondrial disorders (MIDs) but no comprehensive
overview is currently available. This review aims at summarising and discussing findings …

Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) are
established subgroups of mitochondrial encephalomyopathy. m. 3243A> G a common point …