[HTML][HTML] MicroRNAs as biomarkers for prostate cancer prognosis: a systematic review and a systematic reanalysis of public data
Background Reliable prognostic biomarkers to distinguish indolent from aggressive prostate
cancer (PCa) are lacking. Many studies investigated microRNAs (miRs) as PCa prognostic …
cancer (PCa) are lacking. Many studies investigated microRNAs (miRs) as PCa prognostic …
Dissecting miRNA facilitated physiology and function in human breast cancer for therapeutic intervention
MicroRNAs (miRNAs) are key epigenomic regulators of biological processes in animals and
plants. These small non coding RNAs form a complex networks that regulate cellular …
plants. These small non coding RNAs form a complex networks that regulate cellular …
[HTML][HTML] miR‑148a, miR‑152 and miR‑200b promote prostate cancer metastasis by targeting DNMT1 and PTEN expression
V Gurbuz, S Sozen, CY Bilen… - Oncology …, 2021 - spandidos-publications.com
MicroRNAs (miRs) modulate the expression of target genes in the signal pathway on
transcriptome level. The present study investigated the 'epigenetic‑based miRNA (epi …
transcriptome level. The present study investigated the 'epigenetic‑based miRNA (epi …
[HTML][HTML] Emerging role of different DNA methyltransferases in the pathogenesis of cancer
P Liu, F Yang, L Zhang, Y Hu, B Chen… - Frontiers in …, 2022 - frontiersin.org
DNA methylation is one of the most essential epigenetic mechanisms to regulate gene
expression. DNA methyltransferases (DNMTs) play a vital role in DNA methylation in the …
expression. DNA methyltransferases (DNMTs) play a vital role in DNA methylation in the …
[HTML][HTML] Epigenetic silencing of genes enhanced by collective role of reactive oxygen species and MAPK signaling downstream ERK/Snail axis: Ectopic application of …
Loss of E-cadherin and epithelial to mesenchymal transition (EMT) are key steps in cancer
progression. Reactive oxygen species (ROS) play significant roles in cellular physiology and …
progression. Reactive oxygen species (ROS) play significant roles in cellular physiology and …
Regulation of DNA methylation machinery by epi-miRNAs in human cancer: emerging new targets in cancer therapy
MR Karimzadeh, P Pourdavoud, N Ehtesham… - Cancer Gene …, 2021 - nature.com
Disruption in DNA methylation processes can lead to alteration in gene expression and
function that would ultimately result in malignant transformation. In this way, studies have …
function that would ultimately result in malignant transformation. In this way, studies have …
Roles of OCT4 in pathways of embryonic development and cancer progression
SK Patra - Mechanisms of ageing and development, 2020 - Elsevier
Somatic cells may be reprogrammed to pluripotent state by ectopic expression of certain
transcription factors; namely, OCT4, SOX2, KLF4 and c-MYC. However, the molecular and …
transcription factors; namely, OCT4, SOX2, KLF4 and c-MYC. However, the molecular and …
Epigenetics and prostate cancer: defining the timing of DNA methyltransferase deregulation during prostate cancer progression
V Tzelepi, S Logotheti, E Efstathiou, P Troncoso… - Pathology, 2020 - Elsevier
DNA methyltransferases (DNMTs) regulate gene expression by methylating cytosine
residues within CpG dinucleotides. Aberrant methylation patterns have been shown in a …
residues within CpG dinucleotides. Aberrant methylation patterns have been shown in a …
[HTML][HTML] Metformin regulates expression of DNA methyltransferases through the miR-148/-152 family in non-small lung cancer cells
BB Lee, D Kim, Y Kim, J Han, YM Shim, DH Kim - Clinical epigenetics, 2023 - Springer
Background To understand the molecular mechanisms involved in regulation of DNA
methyltransferases (DNMTs) by metformin in non-small cell lung cancer (NSCLC) cells …
methyltransferases (DNMTs) by metformin in non-small cell lung cancer (NSCLC) cells …
[HTML][HTML] Epigenetic perspectives of COVID-19: Virus infection to disease progression and therapeutic control
COVID-19 has caused numerous deaths as well as imposed social isolation and upheaval
world-wide. Although, the genome and the composition of the virus, the entry process and …
world-wide. Although, the genome and the composition of the virus, the entry process and …