P-glycoprotein (P-gp)-driven cancer drug resistance: biological profile, non-coding RNAs, drugs and nanomodulators

Y Guo, M Ashrafizadeh, MM Tambuwala, J Ren… - Drug Discovery …, 2024 - Elsevier
Drug resistance has compromised the efficacy of chemotherapy. The dysregulation of drug
transporters including P-glycoprotein (P-gp) can mediate drug resistance through drug …

Synergistic effects of flavonoids and paclitaxel in cancer treatment: A systematic review

S Asnaashari, E Amjad, B Sokouti - Cancer cell international, 2023 - Springer
Paclitaxel is a natural anticancer compound with minimal toxicity, the capacity to stabilize
microtubules, and high efficiency that has remained the standard of treatment alongside …

Recent Advances in Curcumin-Based Combination Nanomedicines for Cancer Therapy

AR Afshari, M Sanati, P Kesharwani… - Journal of Functional …, 2023 - mdpi.com
Standard cancer chemotherapeutics often produce significant adverse effects and
eventually lose their effectiveness due to the emergence of resistance mechanisms. As a …

The Association Between Anti‐Neoplastic Effects of Curcumin and Urogenital Cancers: A Systematic Review

S Mazaheri-Tehrani, S Rouzbahani… - BioMed Research …, 2024 - Wiley Online Library
Background: Curcumin is a polyphenol compound with anticancer effects. We aimed to
review the anti‐neoplastic effects of curcumin on urogenital cancers, by regulating different …

Epigenetic and biogenetic regulation by polyphenols in prostate cancer in the context of 3P medicine

H Dong, C Zhang - EPMA Journal, 2024 - Springer
Prostate cancer (PCa) can remain asymptomatic for years, complicating early detection and
effective intervention. Predictive, Preventive, and Personalized Medicine (3PM) provides a …

姜黄素增强5-FU 对结直肠癌小鼠移植瘤生长抑制能力的研究.

曹强, 李君 - Journal of Modern Medicine & Health, 2023 - search.ebscohost.com
目的探讨姜黄素联合5-氟尿嘧啶(5-FU) 对结直肠癌(CRC) 小鼠移植瘤生长的影响及可能的分子
机制. 方法将CRC 细胞系SW480 接种于BALB/c 小鼠右腋窝皮下, 建模成功后将小鼠随机分为 …

Enhancing the effectiveness of paclitaxel with stigmasterol bioactive compounds for cancer treatment

HA Hussein, FL Khaphi, RM Jassem - International Journal of Innovative …, 2024 - ijirss.com
This study examines the anticancer activity of stigmasterol bioactive compounds combined
with paclitaxel. Drug resistance and high toxicity in chemotherapy present a challenge in …

[PDF][PDF] Synergistic effects of flavonoids and paclitaxel in cancer treatment: a systematic

S Asnaashari, E Amjad, B Sokouti - 2023 - cancerci.biomedcentral.com
Paclitaxel is a natural anticancer compound with minimal toxicity, the capacity to stabilize
microtubules, and high efficiency that has remained the standard of treatment alongside …

[HTML][HTML] Cytotoxicity of curcumin against CD44±prostate cancer cells: Roles of miR-383 and miR-708

R Panahizadeh, MA Vatankhah, F Jeddi… - Avicenna Journal of …, 2023 - ncbi.nlm.nih.gov
Objective: Cancer stem cells (CSCs) remaining in the tumor tissues after applying treatments
may cause recurrence or metastasis of prostate cancer (PC). Curcumin has the promising …

[HTML][HTML] Regulation of Apoptosis, Autophagy, and Metastasis by Luteolin in Human Bladder Cancer EJ138 Cells: An Experimental Study

MA Vatankhah, A Ziyabakhsh, MV Ojarood - IJ Pharmaceutical Research - brieflands.com
Background: Chemotherapy remains a primary approach to cancer treatment, widely
applied in bladder cancer (BC). However, the various side effects and resistance associated …