Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …

Repair of damaged skeletal‐muscle tissue is limited by the regenerative capacity of the
native tissue. Current clinical approaches are not optimal for the treatment of large …

Biochemical and biophysical cues directly affect cell morphology, adhesion, proliferation,
and phenotype, as well as differentiation; thus, they have been commonly utilized for …

Hamstring strain injuries remain a challenge for both athletes and clinicians, given their high
incidence rate, slow healing, and persistent symptoms. Moreover, nearly one third of these …

Platelet rich plasma (PRP) is a powerful new biologic tool in sports medicine. PRP is a
fraction of autologous whole blood containing and increased number of platelets and a wide …

Skeletal muscle has the capacity of regeneration after injury. However, for large volumes of
muscle loss, this regeneration needs interventional support. Consequently, muscle injury …

Mechanotransduction is the physiological process where cells sense and respond to
mechanical loads. This paper reclaims the term “mechanotherapy” and presents the current …

Skeletal muscle injuries typically result from traumatic incidents such as combat injuries
where soft-tissue extremity injuries are present in one of four cases. Further, about 4.5 …

Millions of Americans suffer from skeletal muscle injuries annually that can result in
volumetric muscle loss (VML), where extensive musculoskeletal damage and tissue loss …

Cell behaviors are influenced by the surrounding dynamic microenvironment where the
extracellular matrix (ECM) composed of different micro/nano-structures plays a key role …