Prognostic biomarkers in diffuse large B-cell lymphoma
IS Lossos, D Morgensztern - Journal of clinical oncology, 2006 - ascopubs.org
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's
lymphoma. Although it represents a curable disease, less than half of the patients are cured …
lymphoma. Although it represents a curable disease, less than half of the patients are cured …
Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies
D Thomalla, L Beckmann, C Grimm… - Blood, The Journal …, 2022 - ashpublications.org
The BCL2 inhibitor venetoclax has been approved to treat different hematological
malignancies. Because there is no common genetic alteration causing resistance to …
malignancies. Because there is no common genetic alteration causing resistance to …
Cancer chemotherapy
DL Gustafson, RL Page - Withrow and MacEwen's small animal …, 2013 - books.google.com
The use of chemical elixirs for the treatment of cancer can be traced through the medicinal
customs and practices of a number of cultures. 1 The modern use of pharmacologic agents …
customs and practices of a number of cultures. 1 The modern use of pharmacologic agents …
The significance of TP53 in lymphoid malignancies: mutation prevalence, regulation, prognostic impact and potential as a therapeutic target
KJJ Cheung, DE Horsman… - British journal of …, 2009 - Wiley Online Library
The tumour suppressor TP53 (previously termed p53) mediates a pathway that is
considered to be one of the most important mechanisms in the maintenance of genomic …
considered to be one of the most important mechanisms in the maintenance of genomic …
[HTML][HTML] Evaluation of immunophenotype in diffuse large B-cell lymphoma and its impact on prognosis
M Berglund, U Thunberg, RM Amini, M Book, G Roos… - Modern pathology, 2005 - Elsevier
Diffuse large B-cell lymphoma (DLBCL) has been shown to be comprised of at least two
prognostic entities, depending on its resemblance to normal germinal center or activated B …
prognostic entities, depending on its resemblance to normal germinal center or activated B …
P53 expression correlates with poorer survival and augments the negative prognostic effect of MYC rearrangement, expression or concurrent MYC/BCL2 expression …
XJ Wang, L Jeffrey Medeiros, CE Bueso-Ramos… - Modern …, 2017 - nature.com
In patients with diffuse large B-cell lymphoma, MYC rearrangement (MYC-R), MYC
expression, or concurrent expression of MYC and BCL2 is associated with a poorer …
expression, or concurrent expression of MYC and BCL2 is associated with a poorer …
Primary breast non‐Hodgkin's lymphoma: a large single center study of initial characteristics, natural history, and prognostic factors
P Validire, M Capovilla, B Asselain… - American journal of …, 2009 - Wiley Online Library
The aims of this study were to define the initial pathological and clinical characteristics, and
prognostic factors of patients with primary breast malignant lymphoma (PBL). All patients …
prognostic factors of patients with primary breast malignant lymphoma (PBL). All patients …
BCL2, BCL6, MYC, MALT 1, and BCL10 rearrangements in nodal diffuse large B-cell lymphomas: a multicenter evaluation of a new set of fluorescent in situ …
MG Tibiletti, V Martin, B Bernasconi, B Del Curto… - Human pathology, 2009 - Elsevier
Diffuse large B-cell lymphoma is the most common type of non-Hodgkin lymphoma.
Although it is a curable disease, fewer than half of patients are cured with conventional …
Although it is a curable disease, fewer than half of patients are cured with conventional …
[HTML][HTML] Expression of PKC-beta or cyclin D2 predicts for inferior survival in diffuse large B-cell lymphoma
CP Hans, DD Weisenburger, TC Greiner, WC Chan… - Modern pathology, 2005 - Elsevier
We sought to determine whether identification of poor-risk subgroups of diffuse large B-cell
lymphoma (DLBCL) using immunohistochemical stains would have practical utility with …
lymphoma (DLBCL) using immunohistochemical stains would have practical utility with …
[HTML][HTML] Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis
P Wang, P Wang, B Liu, J Zhao, Q Pang, SG Agrawal… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Translocation of the pro-apoptotic protein Bax from the cytosol to the mitochondria is a
crucial step in DNA damage-mediated apoptosis, and is also found to be involved in …
crucial step in DNA damage-mediated apoptosis, and is also found to be involved in …