The development and assembly of the Drosophila adult ventral nerve cord

L Venkatasubramanian, RS Mann - Current opinion in neurobiology, 2019 - Elsevier
In order to generate complex motor outputs, the nervous system integrates multiple sources
of sensory information that ultimately controls motor neurons to generate coordinated …

Retrograde semaphorin–plexin signalling drives homeostatic synaptic plasticity

BO Orr, RD Fetter, GW Davis - Nature, 2017 - nature.com
Homeostatic signalling systems ensure stable but flexible neural activity and animal
behaviour,,,. Presynaptic homeostatic plasticity is a conserved form of neuronal homeostatic …

Functions of plexins/neuropilins and their ligands during hippocampal development and neurodegeneration

V Gil, JA Del Río - Cells, 2019 - mdpi.com
There is emerging evidence that molecules, receptors, and signaling mechanisms involved
in vascular development also play crucial roles during the development of the nervous …

Stereotyped terminal axon branching of leg motor neurons mediated by IgSF proteins DIP-α and Dpr10

L Venkatasubramanian, Z Guo, S Xu, L Tan, Q Xiao… - Elife, 2019 - elifesciences.org
For animals to perform coordinated movements requires the precise organization of neural
circuits controlling motor function. Motor neurons (MNs), key components of these circuits …

Single-cell analysis of innate spinal cord regeneration identifies intersecting modes of neuronal repair

VM Saraswathy, L Zhou, MH Mokalled - Nature communications, 2024 - nature.com
Adult zebrafish have an innate ability to recover from severe spinal cord injury. Here, we
report a comprehensive single nuclear RNA sequencing atlas that spans 6 weeks of …

GABAergic inhibition of leg motoneurons is required for normal walking behavior in freely moving Drosophila

SBM Gowda, PD Paranjpe, OV Reddy… - Proceedings of the …, 2018 - National Acad Sciences
Walking is a complex rhythmic locomotor behavior generated by sequential and periodical
contraction of muscles essential for coordinated control of movements of legs and leg joints …

Modulation of flight and feeding behaviours requires presynaptic IP3Rs in dopaminergic neurons

A Sharma, G Hasan - Elife, 2020 - elifesciences.org
Innate behaviours, although robust and hard wired, rely on modulation of neuronal circuits,
for eliciting an appropriate response according to internal states and external cues …

Drosophila larval to pupal switch under nutrient stress requires IP3R/Ca2+ signalling in glutamatergic interneurons

S Jayakumar, S Richhariya, OV Reddy, MJ Texada… - Elife, 2016 - elifesciences.org
Neuronal circuits are known to integrate nutritional information, but the identity of the circuit
components is not completely understood. Amino acids are a class of nutrients that are vital …

Identification of a single pair of interneurons for bitter taste processing in the Drosophila brain

AA Bohra, BR Kallman, H Reichert, K VijayRaghavan - Current Biology, 2018 - cell.com
Drosophila has become an excellent model system for investigating the organization and
function of the gustatory system due to the relatively simple neuroanatomical organization of …

Fully automated leg tracking of Drosophila neurodegeneration models reveals distinct conserved movement signatures

S Wu, KJ Tan, LN Govindarajan, JC Stewart, L Gu… - PLoS …, 2019 - journals.plos.org
Some neurodegenerative diseases, like Parkinsons Disease (PD) and Spinocerebellar
ataxia 3 (SCA3), are associated with distinct, altered gait and tremor movements that are …