Hygiene hypothesis and autoimmune diseases: A narrative review of clinical evidences and mechanisms
Since the start of the “modern era”, characterized by the increase in urbanization, a
progressive attention to hygiene and autoimmune conditions has considerably grown …
progressive attention to hygiene and autoimmune conditions has considerably grown …
Experimental human hookworm infection: a narrative historical review
PR Chapman, P Giacomin, A Loukas… - PLoS Neglected …, 2021 - journals.plos.org
In 1896, a serendipitous laboratory accident led to the understanding that hookworms
propagate infection by penetrating skin, a theory that was then confirmed with the first …
propagate infection by penetrating skin, a theory that was then confirmed with the first …
Eosinophils and helminth infection: protective or pathogenic?
Since the earliest descriptions of this enigmatic cell, eosinophils have been implicated in
both protective and pathogenic immune responses to helminth infection. Nevertheless …
both protective and pathogenic immune responses to helminth infection. Nevertheless …
Role of environmental factors in multiple sclerosis
Introduction Environmental factors play a significant role in the pathogenesis and
progression of multiple sclerosis (MS), either acting alone or by interacting with other …
progression of multiple sclerosis (MS), either acting alone or by interacting with other …
Effect of experimental hookworm infection on insulin resistance in people at risk of type 2 diabetes
The reduced prevalence of insulin resistance and type 2 diabetes in countries with endemic
parasitic worm infections suggests a protective role for worms against metabolic disorders …
parasitic worm infections suggests a protective role for worms against metabolic disorders …
Helminth-derived biomacromolecules as therapeutic agents for treating inflammatory and infectious diseases: What lessons do we get from recent findings?
Despite the tremendous progress in healthcare sectors, a number of life-threatening
infectious, inflammatory, and autoimmune diseases are continuously challenging mankind …
infectious, inflammatory, and autoimmune diseases are continuously challenging mankind …
Helicobacter pylori infection and risk of multiple sclerosis: An updated meta‐analysis
Background There is considerable controversy around the question as to whether
Helicobacter pylori (H. pylori) infection has a protective or causative role in the development …
Helicobacter pylori (H. pylori) infection has a protective or causative role in the development …
Immune system investigation using parasitic helminths
Coevolutionary adaptation between humans and helminths has developed a finely tuned
balance between host immunity and chronic parasitism due to immunoregulation. Given that …
balance between host immunity and chronic parasitism due to immunoregulation. Given that …
Experimental infection with the hookworm, Necator americanus, is associated with stable gut microbial diversity in human volunteers with relapsing multiple sclerosis
TP Jenkins, DI Pritchard, R Tanasescu, G Telford… - BMC biology, 2021 - Springer
Background Helminth-associated changes in gut microbiota composition have been
hypothesised to contribute to the immune-suppressive properties of parasitic worms …
hypothesised to contribute to the immune-suppressive properties of parasitic worms …
Helminth lessons in inflammatory bowel diseases (IBD)
T Atagozli, DE Elliott, MN Ince - Biomedicines, 2023 - mdpi.com
Helminths are multicellular invertebrates that colonize the gut of many vertebrate animals
including humans. This colonization can result in pathology, which requires treatment. It can …
including humans. This colonization can result in pathology, which requires treatment. It can …