[HTML][HTML] The antithrombotic activity of natural and synthetic coumarins
Thrombosis, which seriously endangers human health and life, is the leading cause of
morbidity and mortality globally. Antithrombotic drugs can interfere with the occurrence and …
morbidity and mortality globally. Antithrombotic drugs can interfere with the occurrence and …
Synthetic coumarin derivatives with anticoagulation and antiplatelet aggregation inhibitory effects
Thrombosis is the leading cause of illness and mortality worldwide, posing a serious risk to
human health and life. Because antithrombotic drugs can prevent the beginning and …
human health and life. Because antithrombotic drugs can prevent the beginning and …
A narrative review of benzo-fused coumarins, shedding light on their medicinal activities
Background: Coumarins and their derivatives excel in chemical diversity, coupled with a
wide variety of biological potentials, and tend to be beneficial to the health of the human …
wide variety of biological potentials, and tend to be beneficial to the health of the human …
Indole-based fibrates as potential hypolipidemic and antiobesity agents
KV Sashidhara, M Kumar, R Sonkar… - Journal of Medicinal …, 2012 - ACS Publications
Hypolipidemic and antiobesity effects of the newly synthesized indole-based fibrates were
evaluated in Triton WR-1339 and high fat diet (HFD)-induced hyperlipidemic rats …
evaluated in Triton WR-1339 and high fat diet (HFD)-induced hyperlipidemic rats …
Discovery of coumarin–dihydropyridine hybrids as bone anabolic agents
KV Sashidhara, M Kumar, V Khedgikar… - Journal of Medicinal …, 2013 - ACS Publications
The concept of molecular hybridization led us to discover a novel series of coumarin–
dihydropyridine hybrids that have potent osteoblastic bone formation in vitro and that …
dihydropyridine hybrids that have potent osteoblastic bone formation in vitro and that …
[HTML][HTML] Coumarin–trioxane hybrids: Synthesis and evaluation as a new class of antimalarial scaffolds
KV Sashidhara, A Kumar, RP Dodda… - Bioorganic & medicinal …, 2012 - Elsevier
First synthesis of novel coumarin–trioxane hybrids is reported. The synthesis was achieved
via condensation of β-hydroxyhydroperoxides with coumarinic-aldehydes in presence of p …
via condensation of β-hydroxyhydroperoxides with coumarinic-aldehydes in presence of p …
[HTML][HTML] A novel route to synthesis of flavones from salicylaldehyde and acetophenone derivatives
Convenient, facile, and alternate synthesis of medicinally important flavones is reported. The
2-hydroxychalcones derived from condensation between acetophenones and …
2-hydroxychalcones derived from condensation between acetophenones and …
[HTML][HTML] A importância das cumarinas para a química medicinal eo desenvolvimento de compostos bioativos nos últimos anos
DP Franco, TM Pereira, F Vitorio, NF Nadur… - Química …, 2021 - SciELO Brasil
Coumarins are natural products characterized as 2H-chromen-2-one, according to IUPAC
nomenclature, largely distributed in plants, as well as, in species of fungi and bacteria …
nomenclature, largely distributed in plants, as well as, in species of fungi and bacteria …
Molecular docking, computational, and antithrombotic studies of novel 1, 3, 4-oxadiazole derivatives
A new series of 1, 3, 4-oxadiazoles derivatives was synthesized, characterized, and
evaluated for their in vitro and in vivo anti-thrombotic activity. Compounds (3a–3i) exhibited …
evaluated for their in vitro and in vivo anti-thrombotic activity. Compounds (3a–3i) exhibited …
Progress in isoindolone alkaloid derivatives from marine microorganism: Pharmacology, preparation, and mechanism
Compound 1 (SMTP-7, also FGFC1), an isoindolone alkaloid from marine fungi Starchbotrys
longispora FG216 and fungi Stachybotrys microspora IFO 30018, possessed diverse …
longispora FG216 and fungi Stachybotrys microspora IFO 30018, possessed diverse …