Allergic diseases are on the rise in the Western world and well-known allergy-protecting and-
driving factors such as microbial and dietary exposure, pollution and smoking mediate their …

Viral respiratory tract infections are associated with asthma inception in early life and asthma
exacerbations in older children and adults. Although how viruses influence asthma inception …

The pathogenesis of allergic rhinitis is associated with genetic, environmental, and
epigenetic factors. Genotyping of single nucleotide polymorphisms (SNPs) is an advanced …

There has been a substantial increase in the incidence and the prevalence of allergic
disorders in the recent decades, which seems to be related to rapid environmental and …

Immunoglobulin E (IgE)-mediated allergy against cow's milk protein fractions such as whey
is one of the most common food-related allergic disorders of early childhood. Histone …

Background Genomewide association studies identified ORMDL 3 as a plausible asthma
candidate gene. ORMDL proteins regulate sphingolipid metabolism and ceramide …

The results of our systematic literature search provide a strong support for the role of
epigenetic mechanisms in (mediating the effects of environmental exposure on) pediatric …

Oral cancer etiology is complex and controlled by multi-factorial events including genetic
events. Candidate gene studies, genome-wide association studies, and next-generation …

Background Allergic rhinitis (AR) is a complex disease, in which gene–environment
interactions contribute to its pathogenesis. Epigenetic modifications such as DNA …

This study describes the role of two STAT 6 gene variants in food allergy using data of
patients and their parents who underwent double‐blind placebo‐controlled food challenges …