[HTML][HTML] Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment

S Peerapornratana, CL Manrique-Caballero… - Kidney international, 2019 - Elsevier
Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

Acute kidney injury in sepsis

R Bellomo, JA Kellum, C Ronco, R Wald… - Intensive care …, 2017 - Springer
Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous
presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU …

Renal microvascular endothelial cell responses in sepsis-induced acute kidney injury

G Molema, JG Zijlstra, M van Meurs… - Nature Reviews …, 2022 - nature.com
Microvascular endothelial cells in the kidney have been a neglected cell type in sepsis-
induced acute kidney injury (sepsis-AKI) research; yet, they offer tremendous potential as …

Paradigms of acute kidney injury in the intensive care setting

JA Kellum, JR Prowle - Nature Reviews Nephrology, 2018 - nature.com
Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies,
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …

Sepsis-associated acute kidney injury

CL Manrique-Caballero… - Critical Care …, 2021 - criticalcare.theclinics.com
Sepsis-associated acute kidney injury (S-AKI) is a common, life-threatening complication in
hospitalized and critically ill patients. S-AKI increases in-hospital mortality 6-fold to 8-fold, 1 …

Acute kidney injury 2016: diagnosis and diagnostic workup

M Ostermann, M Joannidis - Critical care, 2016 - Springer
Acute kidney injury (AKI) is common and is associated with serious short-and long-term
complications. Early diagnosis and identification of the underlying aetiology are essential to …

A unified theory of sepsis-induced acute kidney injury: inflammation, microcirculatory dysfunction, bioenergetics, and the tubular cell adaptation to injury

H Gomez, C Ince, D De Backer, P Pickkers, D Payen… - Shock, 2014 - journals.lww.com
Given that the leading clinical conditions associated with acute kidney injury (AKI), namely,
sepsis, major surgery, heart failure, and hypovolemia, are all associated with shock, it is …

Sepsis-induced acute kidney injury

H Gómez, JA Kellum - Critical care nephrology, 2019 - Elsevier
Sepsis is considered a major public health problem. Despite mortality being associated
consistently with organ compromise, the mechanisms by which sepsis causes multiple …

Acute kidney injury

R Bellomo, JA Kellum, C Ronco - The Lancet, 2012 - thelancet.com
Acute kidney injury (formerly known as acute renal failure) is a syndrome characterised by
the rapid loss of the kidney's excretory function and is typically diagnosed by the …

Mechanisms of organ dysfunction in sepsis

R Pool, H Gomez, JA Kellum - Critical care clinics, 2018 - criticalcare.theclinics.com
Development of organ dysfunction is the most important clinical event during sepsis, as it
directly relates to mortality and morbidity. Although the new definition of sepsis captures this …