[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics

M Fedele, R Piersanti, F Regazzoni, M Salvador… - Computer Methods in …, 2023 - Elsevier
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …

[HTML][HTML] Images as drivers of progress in cardiac computational modelling

P Lamata, R Casero, V Carapella, SA Niederer… - Progress in biophysics …, 2014 - Elsevier
Computational models have become a fundamental tool in cardiac research. Models are
evolving to cover multiple scales and physical mechanisms. They are moving towards …

[HTML][HTML] A cardiac electromechanical model coupled with a lumped-parameter model for closed-loop blood circulation

F Regazzoni, M Salvador, PC Africa, M Fedele… - Journal of …, 2022 - Elsevier
We propose a novel mathematical and numerical model for cardiac electromechanics,
wherein biophysically detailed core models describe the different physical processes …

[图书][B] Mathematical modelling of the human cardiovascular system: data, numerical approximation, clinical applications

A Quarteroni, A Manzoni, C Vergara - 2019 - books.google.com
Mathematical and numerical modelling of the human cardiovascular system has attracted
remarkable research interest due to its intrinsic mathematical difficulty and the increasing …

[HTML][HTML] Electromechanical modeling of human ventricles with ischemic cardiomyopathy: numerical simulations in sinus rhythm and under arrhythmia

M Salvador, M Fedele, PC Africa, E Sung… - Computers in Biology …, 2021 - Elsevier
We developed a novel patient-specific computational model for the numerical simulation of
ventricular electromechanics in patients with ischemic cardiomyopathy (ICM). This model …

Cardiac dysfunction in heart failure: the cardiologist's love affair with time

DL Brutsaert - Progress in cardiovascular diseases, 2006 - Elsevier
Translating research into clinical practice has been a challenge throughout medical history.
From the present review, it should be clear that this is particularly the case for heart failure …

Transmural dispersion of myofiber mechanics: implications for electrical heterogeneity in vivo

H Ashikaga, BA Coppola, B Hopenfeld… - Journal of the American …, 2007 - jacc.org
Objectives: We investigated whether transmural mechanics could yield insight into the
transmural electrical sequence. Background: Although the concept of transmural dispersion …

A monolithic algorithm for the simulation of cardiac electromechanics in the human left ventricle

A Gerbi, L Dedè, A Quarteroni - Mathematics in Engineering, 2018 - infoscience.epfl.ch
In this paper, we propose a monolithic algorithm for the numerical solution of the
electromechanics model of the left ventricle in the human heart. Our coupled model …

An intergrid transfer operator using radial basis functions with application to cardiac electromechanics

M Salvador, L Dede', A Quarteroni - Computational Mechanics, 2020 - Springer
In the framework of efficient partitioned numerical schemes for simulating multiphysics PDE
problems, we propose using intergrid transfer operators based on radial basis functions to …

Heterogeneity of left ventricular wall thickening mechanisms

A Cheng, TC Nguyen, M Malinowski, GT Daughters… - Circulation, 2008 - Am Heart Assoc
Background—Myocardial fibers are grouped into lamina (or sheets) 3 to 4 cells thick. Fiber
shortening produces systolic left ventricular (LV) wall thickening primarily by laminar …