Molecular mechanisms of neuroinflammation in aging and Alzheimer's disease progression

FL Andronie-Cioara, AI Ardelean… - International journal of …, 2023 - mdpi.com
Aging is the most prominent risk factor for late-onset Alzheimer's disease. Aging associates
with a chronic inflammatory state both in the periphery and in the central nervous system, the …

Nanomedicine-based technologies and novel biomarkers for the diagnosis and treatment of Alzheimer's disease: from current to future challenges

A Cano, P Turowski, M Ettcheto, JT Duskey… - Journal of …, 2021 - Springer
Increasing life expectancy has led to an aging population, which has consequently
increased the prevalence of dementia. Alzheimer's disease (AD), the most common form of …

Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development

BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …

The link between oxidative stress, mitochondrial dysfunction and neuroinflammation in the pathophysiology of Alzheimer's disease: therapeutic implications and future …

MC Jurcău, FL Andronie-Cioara, A Jurcău, F Marcu… - Antioxidants, 2022 - mdpi.com
Alzheimer's disease (AD), the most common form of dementia, has increasing incidence,
increasing mortality rates, and poses a huge burden on healthcare. None of the currently …

In Vitro and In Vivo Comparison of Curcumin-Encapsulated Chitosan-Coated Poly(lactic-co-glycolic acid) Nanoparticles and Curcumin/Hydroxypropyl-β …

L Zhang, S Yang, LR Wong, H Xie… - Molecular …, 2020 - ACS Publications
Curcumin (CUR) has antioxidant and anti-inflammatory effects that are beneficial to
Alzheimer's disease (AD). However, the poor solubility and high instability of CUR …

Functionalization strategies of polymeric nanoparticles for drug delivery in Alzheimer's disease: Current trends and future perspectives

L La Barbera, E Mauri, M D'Amelio… - Frontiers in neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD), the most common form of dementia, is a progressive and
multifactorial neurodegenerative disorder whose primary causes are mostly unknown. Due …

Oligomerization and conformational change turn monomeric β-amyloid and tau proteins toxic: Their role in Alzheimer's pathogenesis

B Penke, M Szűcs, F Bogár - Molecules, 2020 - mdpi.com
The structural polymorphism and the physiological and pathophysiological roles of two
important proteins, β-amyloid (Aβ) and tau, that play a key role in Alzheimer's disease (AD) …

Nanomaterials toward the treatment of Alzheimer's disease: Recent advances and future trends

H Zeng, Y Qi, Z Zhang, C Liu, W Peng, Y Zhang - Chinese chemical letters, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive and fatal neurodegenerative condition and the
most prevalent cause of dementia. This disease is characterized by progressive cognitive …

Polyphenols in Alzheimer's disease and in the gut–brain axis

VP Reddy, P Aryal, S Robinson, R Rafiu, M Obrenovich… - Microorganisms, 2020 - mdpi.com
Polyphenolic antioxidants, including dietary plant lignans, modulate the gut–brain axis,
which involves transformation of these polyphenolic compounds into physiologically active …

Effects of chemical modification and nanotechnology on wood properties

W Bi, H Li, D Hui, M Gaff, R Lorenzo, I Corbi… - Nanotechnology …, 2021 - degruyter.com
As a green material, wood is widely used in building decoration, railway construction, and
other fields. However, the wood itself has inherent defects of being easy to absorb water and …