Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …

The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Molecular profiling of circulating extracellular vesicles (EVs) provides a promising
noninvasive means to diagnose, monitor, and predict the course of metastatic breast cancer …

Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …

The advent of SELEX (systematic evolution of ligands by exponential enrichment)
technology has shown the ability to evolve artificial ligands with affinity and specificity able to …

Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

Microfluidics has become a mature technology, providing an excellent toolbox for the
handling and manipulation of fluid samples, suspended cells, and particles. About 30 years …

Assays for cancer diagnosis via the analysis of biomarkers on circulating extracellular
vesicles (EVs) typically have lengthy sample workups, limited throughput or insufficient …

Effective screening modalities are currently available for only a small subset of cancers, and
they generally have suboptimal performance with complicated procedures. Therefore, there …

Molecular profiling of tumor-derived extracellular vesicles (tEVs) holds great promise for non-
invasive cancer diagnosis. However, sensitive and accurate identification of tEVs is …