Despite the low rate of inherent TP53 mutations, p53 pathway inactivation is a common
denominator in childhood blastomas. Exploiting p53 and its regulators is likely to translate …

Variations in nucleotide excision repair pathway genes may predispose to initiation of
cancers. However, polymorphisms of ERCC1/XPF genes and neuroblastoma risk have not …

Neuroblastoma is a commonly occurring extracranial pediatric solid tumor without defined
etiology. Polymorphisms in pre-miRNAs have been demonstrated to associate with the risk …

The purpose of this paper is to demonstrate that a Bayesian network (BN) approach can
explore hierarchical biophysical relationships that influence tumor response and predict …

Neuroblastoma is one of the most commonly diagnosed solid cancers for children, and
genetic factors may play a critical role in neuroblastoma development. Previous genome …

Neuroblastoma is the third most common childhood cancer after leukemias and cancer of
the central nervous system. Long noncoding RNA MEG3 polymorphisms have been shown …

Nucleotide excision repair (NER) is an essential mechanism of the body to defend against
exogenous carcinogen-induced DNA damage. Defects in NER may impair DNA repair …

Neuroblastoma, which accounts for approximately 10% of all pediatric cancer-related
deaths, has become a therapeutic challenge and global burden attributed to poor outcomes …

BACKGROUND Neuroblastoma is the most frequently diagnosed extracranial solid tumor in
children. Previous studies have shown that single‐nucleotide polymorphisms in some genes …

Alternative splicing (AS) constitutes a major reason for messenger RNA (mRNA) and protein
diversity. Increasing studies have shown a link to splicing dysfunction associated with …