Multigenerational and transgenerational effects of paternal exposure to drugs of abuse on behavioral and neural function
LR Goldberg, TJ Gould - European Journal of Neuroscience, 2019 - Wiley Online Library
Addictions are highly heritable disorders, with heritability estimates ranging from 39% to
72%. Multiple studies suggest a link between paternal drug abuse and addiction in their …
72%. Multiple studies suggest a link between paternal drug abuse and addiction in their …
The role of zebrafish and laboratory rodents in schizophrenia research
V Langova, K Vales, P Horka, J Horacek - Frontiers in Psychiatry, 2020 - frontiersin.org
Schizophrenia is a severe disorder characterized by positive, negative and cognitive
symptoms, which are still not fully understood. The development of efficient antipsychotics …
symptoms, which are still not fully understood. The development of efficient antipsychotics …
Menin deficiency leads to depressive-like behaviors in mice by modulating astrocyte-mediated neuroinflammation
Astrocyte dysfunction and inflammation are associated with the pathogenesis of major
depressive disorder (MDD). However, the mechanisms underlying these effects remain …
depressive disorder (MDD). However, the mechanisms underlying these effects remain …
Hydrogen sulfide alleviates the anxiety-like and depressive-like behaviors of type 1 diabetic mice via inhibiting inflammation and ferroptosis
Y Wang, S Wang, Y Xin, J Zhang, S Wang, Z Yang… - Life sciences, 2021 - Elsevier
Studies reported that sodium hydrosulfide (NaHS) can remit the depressive-like and anxiety-
like behaviors induced by type 1 diabetes mellitus (T1DM). However, the mechanism is still …
like behaviors induced by type 1 diabetes mellitus (T1DM). However, the mechanism is still …
Neurochemical and molecular characterization of ketamine-induced experimental psychosis model in mice
Ketamine, an NMDA receptor antagonist has been shown to induce aberrant behaviour
phenotypes in rodents, some of which are known to simulate the behaviour abnormalities …
phenotypes in rodents, some of which are known to simulate the behaviour abnormalities …
Scn2a haploinsufficient mice display a spectrum of phenotypes affecting anxiety, sociability, memory flexibility and ampakine CX516 rescues their hyperactivity
T Tatsukawa, M Raveau, I Ogiwara, S Hattori… - Molecular Autism, 2019 - Springer
Background Mutations of the SCN2A gene encoding a voltage-gated sodium channel alpha-
II subunit Nav1. 2 are associated with neurological disorders such as epilepsy, autism …
II subunit Nav1. 2 are associated with neurological disorders such as epilepsy, autism …
Nano-particle delivery of brain derived neurotrophic factor after focal cerebral ischemia reduces tissue injury and enhances behavioral recovery
Background Low levels of brain-derived neurotrophic factor (BDNF) are linked to delayed
neurological recovery, depression, and cognitive impairment following stroke …
neurological recovery, depression, and cognitive impairment following stroke …
Behavioral alterations in long-term Toxoplasma gondii infection of C57BL/6 mice are associated with neuroinflammation and disruption of the blood brain barrier
L Castaño Barrios, AP Da Silva Pinheiro, D Gibaldi… - Plos one, 2021 - journals.plos.org
The Apicomplexa protozoan Toxoplasma gondii is a mandatory intracellular parasite and
the causative agent of toxoplasmosis. This illness is of medical importance due to its high …
the causative agent of toxoplasmosis. This illness is of medical importance due to its high …
Behavioral tasks evaluating schizophrenia-like symptoms in animal models: a recent update
MJ Ang, S Lee, JC Kim, SH Kim… - Current …, 2021 - ingentaconnect.com
Background: Schizophrenia is a serious mental illness that affects more than 21 million
people worldwide. Both genetics and the environment play a role in its etiology and …
people worldwide. Both genetics and the environment play a role in its etiology and …
[HTML][HTML] Effect of alpha-mangostin in the prevention of behavioural and neurochemical defects in methylmercury-induced neurotoxicity in experimental rats
Methylmercury (MeHg+) is a known neurotoxin that causes progressive motor neuron
degeneration in the central nervous system. Axonal degeneration, oligodendrocyte …
degeneration in the central nervous system. Axonal degeneration, oligodendrocyte …