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Here we present a review of the literature of influenza modeling studies, and discuss how
these models can provide insights into the future of the currently circulating novel strain of …

Nonpharmaceutical interventions (NPIs) intended to reduce infectious contacts between
persons form an integral part of plans to mitigate the impact of the next influenza pandemic …

Viral protein homeostasis depends entirely on the machinery of the infected cell.
Accordingly, viruses can illuminate the interplay between cellular proteostasis components …

Background Social distancing interventions such as school closure and prohibition of public
gatherings are present in pandemic influenza preparedness plans. Predicting the …

A fractional MSEIR model is presented, involving the Caputo fractional derivative. The
equilibrium points and the basic reproduction number are computed. An analysis of the local …

An emerging disease is one infectious epidemic caused by a newly transmissible pathogen,
which has either appeared for the first time or already existed in human populations, having …

Coronaviruses, which are single stranded, positive sense RNA viruses, are responsible for a
wide variety of existing and emerging diseases in humans and other animals. The …

We extend the existing work on the time-optimal control of the basic SIR epidemic model
with mass action contact rate. Previous results have focused on minimizing an objective …

ABSTRACT A key question in pandemic influenza is the relative roles of innate immunity
and target cell depletion in limiting primary infection and modulating pathology. Here, we …