A comprehensive review on pharmacological activities of pachypodol: A bioactive compound of an aromatic medicinal plant Pogostemon cablin Benth

S Fatima, I Farzeen, A Ashraf, B Aslam, MU Ijaz… - Molecules, 2023 - mdpi.com
As is well known, plant products have been increasingly utilized in the pharmaceutical
industry in recent years. By combining conventional techniques and modern methodology …

Toxic effects of per-and polyfluoroalkyl substances on sperm: Epidemiological and experimental evidence

Z Sun, Y Wen, B Wang, S Deng, F Zhang… - Frontiers in …, 2023 - frontiersin.org
As emerging organic contaminants, per-and polyfluoroalkyl substances (PFASs) have
aroused worldwide concern due to their environmental persistence, ubiquitous presence …

Natural pachypodol integrated, lung targeted and inhaled lipid nanomedicine ameliorates acute lung injury via anti-inflammation and repairing lung barrier

ZC Sun, R Liao, C Xian, R Lin, L Wang, Y Fang… - Journal of Controlled …, 2024 - Elsevier
Acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) is a high-mortality
disease caused by multiple disorders such as COVID-19, influenza, and sepsis. Current …

Sodium p-perfluorous nonenoxybenzene sulfonate induces ROS-mediated necroptosis by directly targeting catalase in HepG2 cells

Y Ye, B Liu, Z Wang, L Liu, Q Zhang, Q Zhang… - Science of The Total …, 2024 - Elsevier
Sodium p-perfluorous nonenoxybenzene sulfonate (OBS) has been widely used as a
substitute for perfluorooctane sulfonic acid (PFOS) because of its high surface activity and …

Isorhamnetin: a flavonoid, attenuated doxorubicin-induced testicular injury via regulation of steroidogenic enzymes and apoptotic signaling gene expression in male …

S Mustafa, MU Ijaz, Q ul Ain, T Afsar… - Toxicology …, 2022 - academic.oup.com
Background Male reproductive damage is one of the most adverse side effects of
doxorubicin (DOX). Isorhamnetin is a natural flavonoid, which displays remarkable …

Organic anion transporting polypeptide 3a1 is a novel influx pump for Perfluorooctane sulfonate in Sertoli cells and contributes to its reproductive toxicity

T Li, L Jiang, S Zheng, C Qiu, N Zhao, X Lin, H Ren… - Chemosphere, 2023 - Elsevier
Persistent organic pollutant perfluorooctane sulfonate (PFOS) is strongly associated with
male reproductive disorders, but the related mechanisms are still not fully understood. In this …

The role of ferroptosis in the damage of human proximal tubule epithelial cells caused by perfluorooctane sulfonate

P Wang, D Liu, S Yan, Y Liang, J Cui, L Guo, S Ren… - Toxics, 2022 - mdpi.com
Perfluorooctane sulfonate (PFOS) is a typical persistent organic pollutant and environmental
endocrine disruptor that has been shown to be associated with the development of many …

The hepatic antioxidant system damage induced with the cafeteria (CAF) diet is largely counteracted using SCD probiotics during development of male Wistar rats

N Aba, EF Koçpınar, T Ceylani - Nutrients, 2023 - mdpi.com
The cafeteria (CAF) diet, reflective of predominant Western dietary behaviors, is implicated
in hastening weight gain, subsequently resulting in health complications such as obesity …

[HTML][HTML] Rutin attenuated hexachlorobenzene-induced testicular injury via regulation of oxidative stress, steroidogenic enzymes and apoptotic process in male rats

AS Tijani, TM Daba, IA Ubong, O Olufunke… - European Journal of …, 2024 - Elsevier
Hexachlorobenzene (HCB) is a pesticide that is constantly produced as a by-product in
many industrial processes. Rutin (RUT) is a flavonoid found in many plants with numerous …

Rhamnazin ameliorates 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-evoked testicular toxicity by restoring biochemical, spermatogenic and histological profile in male albino …

MU Ijaz, S Mustafa, QU Ain… - Human & …, 2023 - journals.sagepub.com
2, 3, 7, 8 tetrachlorodibenzo-p-dioxin (TCDD) is a potential environmental toxin that has the
ability to affect male reproductive tract. Rhamnazin is a naturally present flavone that …