Role of human brown fat in obesity, metabolism and cardiovascular disease: strategies to turn up the heat

JR Ruiz, B Martinez-Tellez, G Sanchez-Delgado… - Progress in …, 2018 - Elsevier
Human brown adipose tissue (BAT) was re-discovered in 2009 by several independent
groups, who showed that it is present and active in adults, as judged from the profound …

[PDF][PDF] Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men

S Søberg, J Löfgren, FE Philipsen, M Jensen… - Cell Reports …, 2021 - cell.com
The Scandinavian winter-swimming culture combines brief dips in cold water with hot sauna
sessions, with conceivable effects on body temperature. We study thermogenic brown …

[HTML][HTML] Personalizing medicine through hybrid imaging and medical big data analysis

L Papp, CP Spielvogel, I Rausch, M Hacker… - Frontiers in …, 2018 - frontiersin.org
Medical imaging has evolved from a pure visualization tool to representing a primary source
of analytic approaches toward in vivo disease characterization. Hybrid imaging is an integral …

Active brown adipose tissue is associated with a healthier metabolic phenotype in obesity

CT Herz, OC Kulterer, M Prager, C Schmöltzer… - Diabetes, 2022 - Am Diabetes Assoc
Obesity is associated with increasing cardiometabolic morbidity and mortality rates
worldwide. Not everyone with obesity, however, develops metabolic complications. Brown …

Brown adipose tissue prevalence is lower in obesity but its metabolic activity is intact

OC Kulterer, CT Herz, M Prager… - Frontiers in …, 2022 - frontiersin.org
Due to its high metabolic activity, brown adipose tissue (BAT) has become a promising
target for the development of novel treatment concepts for metabolic disease. Despite …

Omega‐6 and omega‐3 oxylipins as potential markers of cardiometabolic risk in young adults

L Jurado‐Fasoli, X Di, I Kohler, FJ Osuna‐Prieto… - …, 2022 - Wiley Online Library
Abstract Objective Omega‐6 and omega‐3 oxylipins are known to play a role in
inflammation and cardiometabolic diseases in preclinical models. The associations between …

The impact of using BARCIST 1.0 criteria on quantification of BAT volume and activity in three independent cohorts of adults

B Martinez-Tellez, KJ Nahon, G Sanchez-Delgado… - Scientific Reports, 2018 - nature.com
Human brown adipose tissue (BAT) is commonly assessed by cold-induced 18F-
fluorodeoxyglucose (FDG) PET-CT using several quantification criteria. Uniform criteria for …

Exercise-induced changes on exerkines that might influence brown adipose tissue metabolism in young sedentary adults

A Mendez-Gutierrez, CM Aguilera… - European Journal of …, 2023 - Taylor & Francis
In rodents, exercise alters the plasma concentration of exerkines that regulate white adipose
tissue (WAT) browning or brown adipose tissue (BAT) metabolism. This study aims to …

Brown adipose tissue activity is reduced in women with polycystic ovary syndrome

FR Oliveira, M Mamede, MF Bizzi… - European Journal of …, 2019 - academic.oup.com
Objective To evaluate whether brown adipose tissue (BAT) activity is altered in women with
polycystic ovary syndrome (PCOS), and whether BAT activity correlates with plasma levels …

No evidence of brown adipose tissue activation after 24 weeks of supervised exercise training in young sedentary adults in the ACTIBATE randomized controlled trial

B Martinez-Tellez, G Sanchez-Delgado… - Nature …, 2022 - nature.com
Exercise modulates both brown adipose tissue (BAT) metabolism and white adipose tissue
(WAT) browning in murine models. Whether this is true in humans, however, has remained …