Biological effects of human exposure to environmental cadmium

M Peana, A Pelucelli, CT Chasapis, SP Perlepes… - Biomolecules, 2022 - mdpi.com
Cadmium (Cd) is a toxic metal for the human organism and for all ecosystems. Cd is
naturally found at low levels; however, higher amounts of Cd in the environment result from …

Low temperature photothermal therapy: Advances and perspectives

K Yang, S Zhao, B Li, B Wang, M Lan, X Song - Coordination Chemistry …, 2022 - Elsevier
Photothermal therapy (PTT) has received increasing attention due to its high selectivity, non-
invasiveness, negligible drug resistance, oxygen independence, and minimal side effects. In …

Fisetin and quercetin: promising flavonoids with chemopreventive potential

D Kashyap, VK Garg, HS Tuli, MB Yerer, K Sak… - Biomolecules, 2019 - mdpi.com
Despite advancements in healthcare facilities for diagnosis and treatment, cancer remains
the leading cause of death worldwide. As prevention is always better than cure, efficient …

A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic …

N Deng, LK Goh, H Wang, K Das, J Tao, IB Tan… - Gut, 2012 - gut.bmj.com
Objective Gastric cancer is a major gastrointestinal malignancy for which targeted therapies
are emerging as treatment options. This study sought to identify the most prevalent …

Harnessing the immune system against cancer: current immunotherapy approaches and therapeutic targets

AR Kumar, AR Devan, B Nair, BS Vinod… - Molecular biology …, 2021 - Springer
Cancer immunotherapy is a rapidly evolving concept that has been given the tag" fifth pillar"
of cancer therapy while radiation therapy, chemotherapy, surgery and targeted therapy …

Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1α and STAT-3

PN Ganji, W Park, J Wen, H Mahaseth, J Landry… - Angiogenesis, 2013 - Springer
Hypoxia-inducible factors (HIFs) and STAT-3 play essential roles in angiogenesis. HIF-1α
and STAT-3 are clients of the heat shock protein 90 (HSP90). We hypothesized that …

[PDF][PDF] Effect of root extracts of medicinal herb Glycyrrhiza glabra on HSP90 gene expression and apoptosis in the HT-29 colon cancer cell line

SM Nourazarian, A Nourazarian… - … Pacific journal of …, 2016 - pdfs.semanticscholar.org
Colorectal cancer is one of the most common lethal cancer types worldwide. In recent years,
widespread and large-scale studies have been done on medicinal plants for anti-cancer …

Heat shock proteins HSPA1 and HSP90AA1 are upregulated in colorectal polyps and can be targeted in cancer cells by anti-inflammatory oxicams with arylpiperazine …

I Szczuka, J Wierzbicki, P Serek, BM Szczęśniak-Sięga… - Biomolecules, 2021 - mdpi.com
Heat shock proteins HSPA1/Hsp70α and HSP90AA1/Hsp90α are crucial for cancer growth
but their expression pattern in colorectal polyps or whether they can be modulated by …

Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells

G Chen, X Zhang, M Zhao, Y Wang, X Cheng, D Wang… - BMC cancer, 2011 - Springer
Background Celastrol is an active ingredient of the traditional Chinese medicinal plant
Tripterygium Wilfordii, which exhibits significant antitumor activity in different cancer models …

Direct targeting of HSP90 with daurisoline destabilizes β-catenin to suppress lung cancer tumorigenesis

XH Huang, X Yan, QH Zhang, P Hong, WX Zhang… - Cancer letters, 2020 - Elsevier
Lung cancer is the most frequent cancer worldwide with a poor prognosis. Identification of
novel cancer targets and useful therapeutic strategies without toxicity are urgently needed …