Evaluating testosterone as a phenotypic integrator: from tissues to individuals to species

SE Lipshutz, EM George, AB Bentz… - Molecular and cellular …, 2019 - Elsevier
Highlights•Testosterone (T) is thought to integrate phenotypes that work well
together.•However, it is not clear how such integration is generated within the organism.•T …

Proposing a neural framework for the evolution of elaborate courtship displays

RW Schwark, MJ Fuxjager, MF Schmidt - Elife, 2022 - elifesciences.org
In many vertebrates, courtship occurs through the performance of elaborate behavioral
displays that are as spectacular as they are complex. The question of how sexual selection …

Evolution of androgen receptors contributes to species variation in androgenic regulation of communication signals in electric fishes

MR Proffitt, X Liu, EA Ortlund, GT Smith - Molecular and Cellular …, 2023 - Elsevier
Hormones and receptors coevolve to generate species diversity in hormone action. We
compared the structure and function of androgen receptors (ARs) across fishes, with a focus …

Sex steroids as mediators of phenotypic integration, genetic correlations, and evolutionary transitions

RM Cox - Molecular and cellular endocrinology, 2020 - Elsevier
In recent decades, endocrinologists have increasingly adopted evolutionary methods and
perspectives to characterize the evolution of the vertebrate endocrine system and leverage it …

Systems biology as a framework to understand the physiological and endocrine bases of behavior and its evolution—From concepts to a case study in birds

MJ Fuxjager, TB Ryder, NM Moody, C Alfonso… - Hormones and …, 2023 - Elsevier
Organismal behavior, with its tremendous complexity and diversity, is generated by
numerous physiological systems acting in coordination. Understanding how these systems …

Evolutionary endocrinology and the problem of Darwin's tangled bank

KA Rosvall - Hormones and Behavior, 2022 - Elsevier
Like Darwin's tangled bank of biodiversity, the endocrine mechanisms that give rise to
phenotypic diversity also exhibit nearly endless forms. This tangled bank of mechanistic …

Androgenic signaling systems and their role in behavioral evolution

MJ Fuxjager, ER Schuppe - The Journal of steroid biochemistry and …, 2018 - Elsevier
Sex steroids mediate the organization and activation of masculine reproductive phenotypes
in diverse vertebrate taxa. However, the effects of sex steroid action in this context vary …

The regulation of birdsong by testosterone: Multiple time-scales and multiple sites of action

BA Alward, CA Cornil, J Balthazart, GF Ball - Hormones and behavior, 2018 - Elsevier
Abstract Contribution to Special Issue on Fast effects of steroids. Sex steroid hormones act
during early development to shape the circuitry upon which these same hormones act in …

Seasonal regulation of behaviour: what role do hormone receptors play?

HE Watts - Proceedings of the Royal Society B, 2020 - royalsocietypublishing.org
Many animals differentially express behaviours across the annual cycle as life stages are
coordinated with seasonal environmental conditions. Understanding of the mechanistic …

Evolution of hormone-phenotype couplings and hormone-genome interactions

RM Cox, MD Hale, TN Wittman, CD Robinson… - Hormones and …, 2022 - Elsevier
When selection favors a new relationship between a cue and a hormonally mediated
response, adaptation can proceed by altering the hormonal signal that is produced or by …