The neuromuscular junction (NMJ) is a highly specialized synapse between a motor neuron
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …

The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron
and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating …

With human median lifespan extending into the 80s in many developed countries, the
societal burden of age-related muscle loss (sarcopenia) is increasing. mTORC1 promotes …

The escalation of life expectancy is accompanied by an increase in the prevalence of age-
related conditions, such as sarcopenia. Sarcopenia, a muscle condition defined by low …

The integrity and preservation of the neuromuscular junction (NMJ), the interface between
the motor neuron and skeletal muscle, is critical for maintaining a healthy skeletal muscle …

Abstract The Dystrophin Glycoprotein Complex (DGC) is a large multi-protein complex that
links cytoskeleton actin to the extracellular matrix. This complex is critical in maintaining the …

Dysregulation of mTOR complex 1 (mTORC1) activity drives neuromuscular junction (NMJ)
structural instability during aging; however, downstream targets mediating this effect have …

Proprioception is sensed by muscle spindles for precise locomotion and body posture.
Unlike the neuromuscular junction (NMJ) for muscle contraction which has been well …

Amyloid-β (Aβ) deposition occurs years before cognitive symptoms appear and is
considered a cause of Alzheimer9s disease (AD). The imbalance of Aβ production and …

Aging is associated with gradual degeneration, in mass and function, of the neuromuscular
system. This process, referred to as “sarcopenia”, is considered a disease by itself, and it …